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    It is probably not the Arduino IDE but some other rogue piece of software, like a GSM modem manager (a modern Arduino sort of looks like one) or a driver for old serial mice. Having the Serial monitor open likely means that the serial device is claimed and unavailable to the undesired program. Commented May 12, 2017 at 19:00
  • Is that in any way an indicator of nefarious software running, or just annoying? I imagine something in the HP Workstation special tools could be trying to do that. Commented May 12, 2017 at 19:29