Issues

• Modernizing .NET Bio for .NET 8/10, a few concurrency fixes, and an offer to help maintain

  dotnetbio/bio#46 · Filter by author ataumutozsoy opened on Sep 27, 2026
  2

• CRAM

  dotnetbio/bio#44 · Filter by author rtenhoor opened on Jun 18, 2025
  2

• Burrows-Wheeler Aligner (BWA) implementation?

  dotnetbio/bio#43 · Filter by author jitterbox opened on Jul 22, 2021

• Order & Orientation of Sequences matters for DeNovo Assembler

  dotnetbio/bio#42 · Filter by author robinemig opened on Apr 26, 2020

• BamParser.Parse() returns null objects in rare instances

  dotnetbio/bio#41 · Filter by author RoboStephen opened on Dec 18, 2019
  2

• Speed bottleneck: Avoid re-parsing bam header when reading many intervals

  dotnetbio/bio#40 · Filter by author RoboStephen opened on Oct 18, 2019
  4

• Clustal Parser

  dotnetbio/bio#39 · Filter by author ryanfalzon opened on Apr 8, 2018

• Three-letter amino acid abbreviations

  dotnetbio/bio#37 · Filter by author acesnik opened on Jan 24, 2018
  2

• GFF version 3 crash

  dotnetbio/bio#35 · Filter by author acesnik opened on Oct 19, 2017

• Mitochondrial genetic code variations

  dotnetbio/bio#34 · Filter by author acesnik opened on Oct 18, 2017
  1

• VCF parser

  dotnetbio/bio#33 · Filter by author acesnik opened on Oct 4, 2017
  2

• Suffix arrays for alignment

  dotnetbio/bio#32 · Filter by author acesnik opened on Oct 3, 2017
  2

• propose - wrapper powershell module for bio.dll

  dotnetbio/bio#29 · Filter by author ghost opened on Apr 20, 2017
  1

• Sequence type parameter required

  dotnetbio/bio#28 · Filter by author TayyabaQamar opened on Apr 11, 2017

• BoyerMoore Updated with example

  dotnetbio/bio#24 · Filter by author agento2 opened on Nov 5, 2016
  5

• FASTA parser doesn't support comments

  dotnetbio/bio#17 · Filter by author flipchart opened on Feb 13, 2016
  3

• Case sensitivity still an issue with nuget packages

  dotnetbio/bio#3 · Filter by author evolvedmicrobe opened on Aug 6, 2015
  1