Latest research
Dysphagia and Oral Health in Older Adults: Examining Demographic and Clinical Associations
in DysphagiaOral health is a modifiable risk factor with significant implications for general health, particularly in the geriatric patient population. Poor oral hygiene has been linked to respiratory disease, aspiration pneumonia, and systemic conditions such...
Phytochemical insights into polyphenols: structure–activity relationships, antibacterial effects in oral health, and therapeutic prospects
Polyphenols have been widely explored for their potential antimicrobial and anti-biofilm properties. This paper highlights the scope of polyphenols against oral pathogens explicitly, in the management of oral infectious diseases (caries and...
Ambulatory treatment strategies for small abscess in colonic diverticulitis: A systematic review and qualitative synthesis
Purpose To evaluate the safety and effectiveness of oral antibiotic therapy for adults with diverticulitis complicated by a small diverticular abscess (pericolic abscess ≤ 4 cm) and assess whether oral treatment may represent a suitable alternative...
The effect of postoperative antibiotics in reducing complications following primary surgical closure of oroantral communications secondary to tooth extraction: a retrospective multicenter study
Objectives Maxillary canine, premolar and molar extractions may result in oroantral communication (OAC). Surgical closure aims to prevent the development of a persistent oroantral fistula (OAF), thereby reducing the risk of maxillary sinusitis. There...
Pharmacological management of knee and hip osteoarthritis stratified by oral nonsteroidal anti-inflammatory drugs safety status
Introduction Knee and hip osteoarthritis are treated with oral nonsteroidal anti-inflammatory drugs (NSAIDs); however, pharmacological management by NSAID safety status remains unclear. We characterized pharmacological treatment patterns across...
Non-prescription supportive care interventions for anticancer therapy-induced oral mucositis: protocol for a systematic review and meta-analysis
Background Oral mucositis (OM) is a common and debilitating complication of anticancer therapies, frequently resulting in pain, nutritional impairment, and potential treatment interruption. While several pharmacologic and device-based interventions...
Pediatric orodispersible nanoparticle delivery: recent innovations and practical challenges
Background Designing age-appropriate oral drug-delivery systems remains a major challenge in pharmaceutical sciences. Conventional solid dosage forms are often unsuitable for pediatric patients because of limited swallowing ability, variable dose...
Non-financial barriers drive oral cancer treatment deferral despite free care in rural Northeast India
in BMC CancerBackground Community-based screening programs for oral precancerous lesions and cancer in low- and middle-income countries frequently encounter high rates of treatment deferral, even when treatment costs are covered. This study examined...
Evaluation of referral patterns to the oral and maxillofacial medicine Department, Faculty of Dentistry, Tabriz University of Medical Sciences: a cross-sectional study
Background Oral and maxillofacial medicine is a dental specialty focused on diagnosing and non-surgically managing diseases of the oral and maxillofacial region. This study evaluated referral patterns to the Oral and Maxillofacial Medicine...
The association between perioperative oral care and adverse clinical events after complex cardiac surgery in children
Background Oral health is closely linked to various clinical complications, and maintaining good oral care has become one of the important interventions to reduce the risk of adverse clinical events. However, the association of oral health care with...
Formulation Development and Human Evaluation of A Mucoadhesive Nanotherapeutic Gel Comprising Curcumin-Encapsulated Chitosan Nanoparticles and Coenzyme Q10 for Oral Leukoplakia
Background This study aimed to develop and preliminarily evaluate a mucoadhesive nanotherapeutic gel in a clinical pilot setting. Curcumin and coenzyme Q10 (CoQ10) possess anti-inflammatory and antioxidant properties; however, their clinical utility...
Engineering the Mucosal Frontier: Nanotechnology-Enabled Transmucosal Drug Delivery System in Emerging Era
Introduction Transmucosal drug delivery systems (TM-DDS) have transformed pharmaceutical sciences from 2020 to the present by utilising vascularised mucosal surfaces, including buccal, nasal, sublingual, vaginal, rectal, and ocular channels, thereby...