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Review
. 2021 Jun;26(3):317-325.
doi: 10.1177/1358863X20977016. Epub 2020 Dec 9.

Assessing health-related quality of life among patients with peripheral artery disease: A review of the literature and focus on patient-reported outcome measures

Aishwarya Raja  1 , John Spertus  2 , Robert W Yeh  1   3   4 , Eric A Secemsky  1   3   4
Affiliations
Review

Assessing health-related quality of life among patients with peripheral artery disease: A review of the literature and focus on patient-reported outcome measures

Aishwarya Raja et al. Vasc Med. 2021 Jun.

Abstract

Peripheral artery disease (PAD) is a progressive atherosclerotic disease associated with high rates of morbidity and mortality. Symptomatic PAD typically presents with claudication, and symptom severity strongly associates with reduced health-related quality of life (HRQoL). Existing treatment strategies for PAD are aimed at reducing symptom severity and improving functional outcomes. However, there is a need to incorporate patient-reported outcome measures (PROMs) into PAD treatment and research in order to provide more patient-centered care. This review will discuss the impact of PAD on HRQoL, existing PROMs available to assess PAD-related HRQoL, utilization of PROMs in research studies and registries, and challenges and solutions related to the integration of PROMs into research and clinical settings.

Keywords: claudication; critical limb ischemia (CLI); outcomes; peripheral artery disease (PAD); quality of life.

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Conflict of interest statement

Declaration of conflicting interests

The authors declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Eric A. Secemsky: Consulting/Speakers Bureau/Advisory Board: Bard, Cook, CSI, Janssen, Medtronic, Philips; Grants to Institution: AstraZeneca, Bard, Boston Scientific, Cook, CSI, Medtronic, Philips. Robert W. Yeh: Consulting/Scientific Advisory Board/Research Grants: Abbott Vascular, AstraZeneca, Boston Scientific, Medtronic; Research Grants: Bard, Cook, Philips. The other authors have nothing to disclose.

Figures

Figure 1.
Figure 1.
Barriers and solutions related to the implementation of PROMs in the clinical setting. EHR, electronic health records; PROMs, patient-reported outcome measures.
See this image and copyright information in PMC

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