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Jonathan Wolf is the co-founder and CEO of ZOE, a science and nutrition company on a…
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Jonathan Wolf shared thisEver wondered what top nutrition scientists put in their shopping basket? Wonder no more. This week, Professor Tim Spector and Professor Sarah Berry reveal exactly what they buy in the supermarket, and why. Tim is one of the world's top 100 most-cited scientists and my scientific co-founder at ZOE. Sarah is Professor of Nutrition at King's College London, Chief Scientist at ZOE, a world leader in large-scale human nutrition studies - and a busy working mum. The supermarket is full of hundreds of breads, endless rows of snacks, and a thousand different yogurts. And almost every one of them carries a health claim: high protein, sugar-free, gluten-free, low-fat, gut-friendly, immune-boosting. We've never had more choice, or less idea what to put in the basket. So together, Tim and Sarah uncover: - What to look for on a loaf of supermarket bread - Which nutrition labels on the front of the pack are worth paying attention to - Why most supermarket kefirs and kombuchas aren't doing what they promise - How swapping to the healthiest versions of these foods can affect your long-term health - And the six rules they use to shop well without reading every label By the end of this episode, you'll know exactly what to reach for on your next shop, and what to leave on the shelf. Link in the comments to listen now.
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Jonathan Wolf shared thisOne-third of older adults who suffer a hip fracture die within 12 months. Another third will never be able to care for themselves again. Hip fractures are the most common serious injury in older adults, but most of us barely think about our bones until they break. Your skeleton isn't a rigid frame just carrying you through life. Bone is a living tissue that constantly rebuilds itself, communicates with your other organs, and plays a vital role in your immune health. And unlike teeth, you can regrow bone, which means declining bone health isn't inevitable. There are things you can start doing today to protect your bones later in life. This week, I'm joined by Professor Elaine Dennison, rheumatologist and Professor of Musculoskeletal Epidemiology at the University of Southampton. She's a world-leading expert in bone health, and her research explores how our bones change throughout life and how best to protect them from childhood to old age. Together, we uncover: - Why bone is one of the busiest organs in your body - The connection between your gut, muscles and bones - What puts bone health at risk, and how to spot it early - How your skeleton changes at every stage of life - What you can start doing today to build stronger bones - And whether the gadgets promising better bone health are worth your time By the end of this episode, you'll think completely differently about your skeleton, and know how to look after the bones that look after you. Link in the comments to listen now.
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Jonathan Wolf shared thisFour scientific studies in the last decade have transformed how nutrition scientists understand food. This week, Professor Tim Spector and Professor Sarah Berry explain why these studies challenged everything they used to believe, and what it means for how we should be eating today. Tim is one of the world's top 100 most-cited scientists and my scientific co-founder at ZOE. Sarah is Professor of Nutrition at King's College London, Chief Scientist at ZOE, and a world leader in large-scale human nutrition studies. Together, they reveal: - The study that produced the biggest surprise in modern nutrition research - What scientists are discovering about common additives in our food - Why traditional measures of what makes a food unhealthy are now out-dated - And why some foods classified as ultra-processed may not carry the same health risks as others By the end of this episode, you'll understand why the dietary guidelines we grew up with contradict the latest evidence, and what that means for your food choices. Link in the comments to listen now.
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Jonathan Wolf shared thisWhen I was growing up, I was told that stress was an excuse for wimps. Now, new scientific research shows that certain types of stress can make us sick and shorten our lives. For most of human history, our body's stress response was the difference between life and death. It was built to switch on in seconds, and off again as quickly. Hundreds of thousands of years later, the predator has changed form. Now it's an overflowing inbox, a mortgage payment, a sleepless night, or a meeting you're already late for. And these threats can continue for months or years. So what happens when a survival mechanism built for short bursts stays switched on? This week, I'm joined by Dr Carmine Pariante, a Professor of Biological Psychiatry at King's College London and board-certified consultant psychiatrist. Carmine is one of the world's leading researchers on stress, publishing hundreds of papers on the links between stress, the brain, mental health, and inflammation. This was an incredibly interesting and practical episode which upended what I was brought up to believe. Carmine reveals: - What happens inside your brain and body when you feel stressed - Why chronic stress affects everything from sleep and appetite to inflammation and mental health - How much we should worry about cortisol - What the science says about “cortisol face”, “cortisol belly” and the latest cortisol hacks - And evidence-based ways to handle chronic stress By the end of this episode, you’ll understand why stress can be so powerful, when it becomes harmful, and what you can do about it. Listen now: https://lnkd.in/eRrik2nT
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Jonathan Wolf shared thisIs fat good or bad for your heart health? A lot of people buy low-fat yogurt and skim milk because they believe cutting back on fat will protect their heart. Others are pouring olive oil over everything and cooking with beef fat, convinced that natural, unprocessed fats are the key to a healthy diet. And the rest of us are left wondering: who’s right? After decades of conflicting advice about fat, it’s no wonder so many people are confused about what they should actually be eating. Today, I’m joined by Dr Alice Lichtenstein, one of America's leading researchers on dietary fat and heart health. She has spent decades studying how what we eat influences our cholesterol levels and our risk of heart disease, has published hundreds of scientific papers, and is ranked as one of the top 500 female scientists in the world. She reveals: - Why the low-fat movement of the 1980s may have made our health worse, not better - What saturated fat actually does inside your body, and why not all saturated fats are equal - The truth about beef tallow, seed oils, and grass-fed meat - Whether high-fat diets like keto and carnivore are as healthy as their advocates claim - And the specific foods with the strongest evidence for protecting your heart By the end, you'll know exactly what to eat to protect your heart, and why so much of what we thought we knew about fat turns out to be wrong. Link in the comments to listen now.
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Jonathan Wolf shared thisAround one in four people worldwide have a condition that can cause heart disease, type 2 diabetes, and dementia. And most of them have no idea. Insulin resistance has become a silent epidemic, driven by the ultra processed and high sugar foods we eat today. It can remain completely hidden for years, with no obvious symptoms and no warning signs. Your blood sugar levels might seem fine on the surface, and your weight under control. But left unchecked, it can cause many of the chronic diseases we face today. So how does something so serious go unnoticed for so long? This week, I'm joined by one of the world's leading researchers on the subject - Rob Semple, Professor of Translational Molecular Medicine at the University of Edinburgh and medical doctor. He's published over 100 scientific papers as he has pieced together the story of insulin resistance. Together, we uncover: - Why insulin is one of the most important hormones in your body - How to tell if you might have insulin resistance, and what to do if you do - Why social media's fear of insulin is misguided - The foods, exercises and lifestyle changes with the strongest evidence for reversing it - And the one piece of advice Professor Semple would give anyone looking to improve their metabolic health By the end, you'll have a clear understanding of one of the most overlooked drivers of chronic disease, and the practical steps you can take to protect yourself. Link in the comments to listen now.
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Jonathan Wolf shared thisHow is it possible that a supermodel can have more unhealthy fat than a sumo wrestler? We’ve been taught to think about body fat in simple terms: being thin means being healthy. But today's guest discovered there is a body fat that can remain unseen. It wraps itself around your vital organs, driving inflammation, disrupting your metabolism, and shaping your long-term risk of heart disease, diabetes, and more. And you can carry a significant amount of it without looking overweight. This week, I'm joined by Jimmy Bell, Professor of Molecular Imaging and Metabolism at the University of Westminster, and one of the world's leading experts on the biology of body fat. His research pioneered the use of MRI scanning to understand how and where fat is stored in the body, and what that means for our health. Together, we uncover: - Why two people with identical body weights can have very different health outcomes - What visceral fat is, where it hides, and why it matters - Why BMI is a misleading measure of health - What happens to your body fat when you lose weight - And what you can start doing today to improve your metabolic health from the inside out By the end of this episode, you’ll have a much better understanding of what body fat is, where it is stored, and why the number on the scales doesn’t tell the whole story. Link in the comments to listen now.
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Jonathan Wolf shared thisWe are the first humans in history who decide what goes on our plate. And we're not built for it. For millions of years, food was scarce. You ate what you could find. There was no choice to make. But in an evolutionary blink of an eye, our food landscape has completely changed. We now have an almost infinite range of choices, and a never-ending supply of contradictory advice about which ones to make. Meanwhile, rates of obesity and chronic disease keep rising. So if we're designed for scarcity, how should we eat in a world of abundance? This week, I'm joined by Daniel Lieberman, one of the world's leading paleoanthropologists and a Professor of Biological Sciences at Harvard University, who has spent his career studying the human body through the lens of evolution. He believes that understanding how we evolved is the key to understanding what we should eat, why we gain weight, and why so many modern diets fail. Together, we explore: - Why evolution designed us to crave sugar, fat and salt - What hunter-gatherers ate, and why it isn't the paleo diet - Why your body is so good at storing fat, and so reluctant to let it go - What ultra-processed foods do that our ancestors never had to contend with - And what Daniel learned from putting himself through some of today's most extreme diets By the end, you'll have a completely new way of thinking about food, your body, and what evolution can teach us about eating well in a modern world. Link in the comments to listen now.
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Jonathan Wolf shared thisOne nutrient is linked to a lower risk of heart disease, dementia, and cancer. Yet 95% of people in the US and UK aren't getting enough of it. That nutrient is fiber. For years, it was treated as a boring, unglamorous part of our diet, while the world became obsessed with protein. Now, fiber is back in the spotlight. And new research suggests it may be one of the most powerful tools we have for protecting our long-term health. Joining me this week is Hugh Fearnley-Whittingstall, bestselling author and chef who advocates for seasonal, local produce. Hugh is a household name in the UK, and his TV show River Cottage was instrumental in the UK's organic food movement. Alongside Hugh is Sarah Berry, Professor of Nutrition at King's College London and Chief Scientist at ZOE. Sarah is a world leader in large-scale human nutrition studies and an expert on metabolic health and the importance of food structure. Together, we uncover: - What happens to your gut microbiome when you don't eat enough fiber - Why eating more fiber doesn't have to be expensive or complicated - What the latest science says about why plant diversity matters - Whether "fiber maxxing" is the next big nutrition trend, or just another fad - And the 12 everyday ingredients Hugh believes deserve a place in your kitchen By the end of this episode, you'll know how much fiber you need, why it matters, and the easiest ways to get more of it. Link in the comments to listen now.
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Jonathan Wolf liked thisJonathan Wolf liked thisThis week marks nine years since I joined The Up Group, which has had me thinking a lot about the people who have been part of those nine years and the many who were part of Up long before me. And as we’re pretty well known for our events at Up, it felt about time we did one just for the Up “family”: bringing together people from across the different chapters of the business to celebrate our shared history, the teams that have shaped it and the friendships that have come from it. It was heartwarming having everyone together again and truly inspiring to see how people have gone on to do all sorts of brilliant things across search, investment, technology and some incredible growing businesses. Also, looking around the room, I found myself thinking about what a company really is. It’s easy to think of a business as the thing that exists today: its name, its clients, its team, its offices, its results. In reality, it's more like a patchwork of all the people who have passed through it and left something of themselves behind. For so many of us, Up has been a formative part of our lives. For some, it was a first job. It was where we learnt our trade, made mistakes, found our confidence, worked incredibly hard, laughed a lot, and built friendships that have lasted long after people moved on. So many different people have shaped Up over the years. Everyone added something of their own — and everyone took a little bit of it with them when they left. In that sense, we are all part of Up’s DNA now. And a little bit of Up’s magic has gone with each person into whatever they’ve done next. Nine years on, I feel incredibly lucky to have spent such a big part of my career here, and even luckier for the people I’ve shared it with. For everyone who has been part of Up, past and present: thank you for what you’ve brought to it, what you’ve taught me, and for all the fun we’ve had along the way. Here’s to the Up family — wherever life and work will continue to take us. ❤️ Clare Johnston James Burrows Lizzie Borg Ricky Isaacs Lucy Baker Camille Percheron Ollie George Claire Hogg Jed Butcher Pete Alexander Frankie Greenwell Alex Hazell Johnnie Edmondson Sarah Pipkin Charlotte Woodward Emma Powell Domagoj Landher Tamsin Colsey Koby Dankwah, FCA Harry Wimborne Alexandra Farrell Victoria Welham Isabel Heikkila Eon de Quelen
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Jonathan Wolf liked thisHonored to speak at this virtual conference on Saturday September 19 covering Nutrition and Lifestyle Medicine!! I’ll be speaking about “Diet, Inflammation, and Autoimmunity.” Huge thanks to Dr Shireen Kassam 🌱 for her leadership. Hoping to see you there!! Nutrition and Lifestyle Medicine Conference Plant-Based Health Professionals UK American College of Lifestyle Medicine Stanford University School of Medicine Physicians Committee for Responsible Medicine The Climate Health Society #FoodAsMedicine #PlantBasedDiet #Nutrition #LifestyleMedicine #SustainableDiet Christopher Gardner Jennifer Robinson, PhD Megan Orciari Chris MacAskill Michelle Cen Miguel Ramos Gia Merlo, MD, MBA, MEd Karen Lee Alan Desmond ZOE Federica Amati Jonathan Wolf Peggy Brannigan Emily Senay, MD, MPH Manijeh ('Mani') Berenji, MD, MPH Lisa Patel, MD, MESc Sophie Egan Gemma NewmanJonathan Wolf liked thisMeet the experts! 📣 In less than 20 days, NLMC 2026 Virtual goes live. Join world-leading speakers as they share the latest evidence and practical strategies. Saturday 19th September 2026 Tickets available at → www.nlmc.org.uk
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Jonathan Wolf liked thisThanks Seb - we are trying!Jonathan Wolf liked thisPlural, is by far, one of the most impressive and most interesting VC firms in Europe. Their portfolio has raised $3.3bn this year ALONE. Their mission has always been to back companies that could have a genuine GDP impact in Europe. If you look at their portfolio they really do back insanely unconventional founders building things that could have a transformational impact for the continent. Non-obvious bets that they made a few years ago are now doing insanely well. Across 2026 alone the portfolio has gone on to raise $3.3 billion. Some of the highlights include: 🚀 Helsing raised $1.8bn 🚀 The Exploration Company raised $450m 🚀 Proxima Fusion raised $468m 🚀 OLIX raised $220m 🚀 Callosum raised $100m 🚀 Rivan Industries raised $34m These companies are leading the way in European defence, space exploration, nuclear fusion, chip design etc... industries which most investors weren't looking at a few years ago but have since become mainstream. The team have a remarkable knack for predicting future trends. NICE Carina Namih, Ian Hogarth, Khaled Helioui, Pierre-Dimitri Gore-Coty, Sten Tamkivi and Taavet Hinrikus. Check out my newsletters and podcast here: https://lnkd.in/eKBQw6Ui
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