Vaxign: Vaccine Design

Welcome to Vaxign: Vaccine Design!

Vaxign2 is now available! Click here to try it out.

Note: Sorry that Vaxign and Vaxign2 both have some bug(s) that we are still fixing. Before it is fixed, please download and use the Vaxign-ML-docker for your prediction.

Vaxign (Vaccine Design) is a vaccine target prediction and analysis system based on the principle of reverse vaccinology. Two programs exist in Vaxign: (1) Vaxign Query: provide precomputed Vaxign results for users to explore, and (2) Dynamic Vaxign Analysis: allow sequence input and dynamic Vaxign execution and result visualization.

NOTE: Vaxign is freely available for academic uses. The Vaxign vaccine design pipeline runs some open-access third-party software programs/algorithms in the background. For commercial users, you may want to check all licenses for these third-party programs used in Vaxign.

1. Vaxign Query:

Please cite the following Vaxign references:

He Y, Xiang Z, Mobley HLT. Vaxign: the first web-based vaccine design program for reverse vaccinology and an application for vaccine development.J Biomed Biotechnol. 2010;2010:297505. Epub 2010 Jul [PMID:20671958] [Journal Link]
Xiang Z, He Y. 2009. Vaxign: a web-based vaccine target design program for reverse vaccinology. Procedia in Vaccinology. Volume 1, Issue 1, Pages 23-29.
Xiang Z, He Y. Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology. BMC Bioinformatics. 2013, 14(Suppl 4):S2 (8 March 2013). PMID: 23514126; PMCID: PMC3599071.

Please see the Vaxign Documentation for more information.

Please contact us if you would like to have your favorite genome(s) included in our precomputed Vaxign database. Your suggestions and comments are welcome. Thank you.