Origin and history of howsoever

Old English æfre "ever, at any time, always;" of uncertain origin, no cognates in any other Germanic language; perhaps a contraction of a in feore, literally "ever in life" (the expression a to fore is common in Old English writings). First element is almost certainly related to Old English a "always, ever," from Proto-Germanic *aiwi-, extended form of PIE root *aiw- "vital force, life; long life, eternity." Liberman suggests second element is comparative adjectival suffix -re.

Sometimes contracted to e'er in dialect and poetry. Ever began to be used in late Old English as a way to generalize or intensify when, what, where, etc. The sense evolution was from "at any time at all, in any way" to "at any particular time; at some time or another; under any circumstances." Ever so "to whatever extent" is recorded by 1680s. Expression did you ever? (implying "see/do/hear of such a thing") attested by 1840.

Old English hu "how," from Proto-Germanic *hwo (source also of Old Saxon hwo, Old Frisian, Middle Dutch hu, Dutch hoe, German wie, Gothic hvaiwa "how"), an adverbial form from PIE root *kwo-, stem of relative and interrogative pronouns. Practically a doublet of why, differentiated in form and use.

How come? for "why?" is recorded by 1848 [Bartlett], probably from earlier fuller expressions, e.g. "... how come we to think one thing right in our childhood, and another in our manhood ; how come we to sacrifice one set of opinions to another ...?" [New Monthly Magazine, 1829]; "My father's horses? What! Are they dead. How come they die?" [The Newbernian, Feb. 16, 1838]

Emphatic phrase and how! is recorded from 1865. The formulation was common in book and article titles ("The National Debt, and How to Pay It"), but Pennsylvania writer Bayard Taylor, in whom it is first recorded, seems to have regarded it as a German or German-American expression.

Middle English so, from Old English swa, swæ (adv., conj., pron.) "in this way, in such a manner that," also "to that extent; so as, consequently, therefore," and purely intensive; from Proto-Germanic *swa (source also of Old Saxon, Middle Dutch, Old High German so, Old Norse sva, Danish saa, Swedish så, Old Frisian sa, Dutch zo, German so "so," Gothic swa "as"), from PIE reflexive pronominal stem *swo- "so" (source also of Greek hos "as," Old Latin suad "so," Latin se "himself"), derivative of *s(w)e-, pronoun of the third person and reflexive (see idiom).

Old English swa frequently was strengthened by eall, and so also is contained in compounds as, also, such. The -w- was crushed out by contraction from 12c.; compare two, which underwent the same process but retained its spelling.

As a word confirming a previous statement, late Old English; also from late Old English as an intensive in an affirmative clause (such as so very "exceedingly, extremely"). As an "introductory particle" [OED] from 1590s. Used to add emphasis or contradict a negative from 1913. So in mid-20c. British slang could mean "homosexual" (adj.).

So? as a term of dismissal is attested from 1886 (short for is that so?, etc.); it is older as an abbreviation of is it so? (1803). So what as an exclamation of indifference dates from 1932, perhaps shortened from phrases such as so what of it? etc.

The abbreviating phrase and so forth is attested in Old English; and so on is attested from 1724. So far "at such a distance" was in Middle English; so far so good is from 1721, said then to be a Scottish proverb.