Taconic Biosciences

🧬 In honor of National Psoriasis Awareness Month, we're spotlighting advances in preclinical research that support psoriasis drug development. Our hIL-2 NOG mouse model enables sustained human T cell infiltration and psoriasis-relevant cytokine expression, offering new insight into immune activation and treatment response. 💡 Discover how this model advances psoriasis studies: https://hubs.li/Q03zBSRS0 #PreclinicalResearch #DrugDiscovery #PsoriasisAwarenessMonth

🌟Celebrating World Intern Day! Our interns bring fresh ideas, energy, and curiosity that help drive innovation and growth. Today, we recognize their hard work and the value they add to our team. As Bill Stevens, Vice President of Human Resources and Organizational Development, puts it: "Effective internship programs create value for both the organization and the individual, laying the groundwork for long-term talent development." Thank you to all our interns for your dedication and contributions. You’re shaping the future! #WorldInternDay #TeamTaconic

Streamline Large Knock‑In Model Generation with CRISPR Taconic offers advanced solutions for inserting large DNA segments—like reporter genes, tags, or Cre drivers—without the need for embryonic stem cells. Our advanced CRISPR toolkit allows for: ✔️Efficient integration of large DNA cassettes ✔️Accelerated timelines ✔️Flexibility on genetic background ✔️Support for complex edits in development, disease, and translational research These precision techniques accelerate the creation of humanized models, epitope-tagged proteins, and more. Learn how our CRISPR toolbox can power your next study: https://hubs.li/Q03z7f950 #CRISPR #GenomeEditing #TranslationalResearch #PreclinicalResearch

Discover how Humanized Immune System (HIS) models are shaping the future of drug discovery. Join Philip Dube, PhD, for an insightful discussion on recent advances in humanized mouse models, along with practical strategies to address common challenges and enhance your research outcomes. 🔬 What you’ll learn: ✅ How to choose the right HIS model for your research ✅ Key differences between PBMC and HSC engraftment ✅ Strategies to address limitations in humanized models ✅ How second-gen NOG strains improve immune system function Get expert insights and practical guidance to move your research forward. Register now before it's too late: https://hubs.li/Q03x9Rr00 #PreclinicalResearch #ImmunoOncology #DrugDiscovery

Every research goal deserves the right path to success. At Taconic, we start by understanding your desired outcomes, then align every step to meet that vision with the right genetic modification strategy and breeding plan, ensuring you have the right genetically engineered models to drive your drug discovery forward. Download our eBook to learn how to set your preclinical studies up for success: https://hubs.li/Q03y-1R90 #eBook #DrugDiscovery #PreclinicalResearch #TaconicDrivesDiscovery

Designing a preclinical study? Your sample size matters more than you think. Learn how proper sample size calculations can improve statistical power, model usage, and lead to more reliable results. Author Philip Dube, PhD emphasizes: “While reducing animal use is important, studies must be adequately powered to avoid ambiguous results and ensure scientific and ethical integrity. Appropriate sample sizes are essential for robust, reproducible in vivo research and adherence to the 3Rs principles.” Explore how to design smart, more ethical studies: https://hubs.li/Q03y7bhP0 #TaconicBiosciences #PreclinicalSuccess

Unwind after #AAIC2025 with Taconic and Transpharmation Ltd. at our post-conference happy hour in Toronto! Join us at Steam Whistle Brewing for an evening of craft brews, great food, and insightful conversations with fellow researchers in neuroscience and Alzheimer's disease. Network with scientific leaders from Taconic and Transpharmation, including Joseph Araujo, PhD, Chief Development Officer, and explore innovative in vivo model solutions. 📅 Monday, July 28 | 🕔 5:00–8:30 PM 📍 Steam Whistle Brewing, Toronto 👉 RSVP now: https://hubs.li/Q03y5fXt0 #PreclinicalResearch #TaconicOnTap #HappyHour #Neuroscience

This World Brain Day, discover how Taconic’s Cryopreserved Repository is delivering fast, flexible access to critical models for neurological disease research, worldwide. Alzheimer's (Psen1, Psen2, etc.) and Parkinson's Disease (Human LRRK2 G2019S Rat) models are readily available. ✔️ Transparent licensing for easy access ✔️ Internationally accredited health testing ✔️ Models available within 12 weeks Let’s simplify your path to discovery. https://hubs.li/Q03y57JY0 #Cryopreservation #PreclinicalResearch #WorldBrainDay

Curious about how Humanized Immune System (HIS) models are reshaping preclinical research? Join Taconic's Director of Scientific Marketing, Philip Dube, PhD, as he explores the latest advances in HIS mouse models and their applications in immunology and immuno-oncology. In this #webinar, you'll gain insight into: ✅ Choosing the right HIS model for your research ✅ PBMC vs. HSC engraftment approaches ✅ Addressing common HIS model limitations ✅ Enhanced engraftment in second-gen NOG strains You’ll also get a first look at second-generation NOG strains that support broader immune applications. Register now and take your research to the next level! https://hubs.li/Q03x9Rr00 #PreclinicalResearch #HumanizedModels #DrugDiscovery

🚨New scientific poster with Champions Oncology, Inc. highlights a breakthrough humanized acute myeloid leukemia (AML) model using NOG-EXL mice engrafted with primary AML PDXs and human CD34+ cells. Researchers can now study AML and test immunotherapies in a model that includes human immune cells. 📄 Learn more: https://hubs.li/Q03xgzxy0 #LeukemiaResearch #DrugDiscovery #PreclinicalResearch