Browse Articles

Polycyclic aromatic hydrocarbons are efficient emitters, but achieving desirable properties can be challenging. Here, the authors report the development of monohomotruxene, a nonsymmetric compound with anti-kasha and ultra-long blue phosphorescence.

Here the authors report the results of a multicenter, double-blind, randomized-controlled trial that evaluates the effect and safety of different concentration atropine eyedrops (0.01%, 0.04%, 0.10%) for myopia control in children with high myopia. The findings show that nightly use of 0.10% atropine eye drops for 24 months mitigated myopia progression with an acceptable safety profile.

Aqueous zinc-ion batteries promise safe energy storage but suffer from dendrites and side reactions. Here, authors engineer a zwitterionic fluorinated hydrogel electrolyte to suppress these issues, enabling durable, dendrite free, Ah-level pouch cells.

Here, Pulliam and colleagues characterize the metabolites encoded by tumor-inhabiting microbes and their potential role in cancer pathology.

Reverting waste carbon into chemicals with minimal freshwater use is essential for a sustainable future. Here, the authors engineer the marine bacterium R. nubinhibens, by decoupling bioproduction from central metabolism to convert lignin into chemicals with seawater as a water source.

The realization of high-performance p-type transistors is essential for the realization of next-generation 2D electronics. Here, the authors report the realization of oxygen-doped p-type monolayer WSe₂ transistors with hole mobility over 200 cm² V⁻¹ s⁻¹, contact resistance down to 104 Ω·μm and saturation current densities up to 1635 μA/μm at a drain voltage of -1.2 V.

Protein structures are increasingly available but turning them into useful drug candidates remains difficult. Here, Cao et al. introduce MolGenBench to assess 17 generative methods and reveal gaps in activity, target awareness and generalization.

The process by which the voltage sensor electromechanically couples to the pore in K+ channels is not fully understood. A cryo-EM structure of a partially activated state, together with computational modeling and MD simulations, clarifies the mechanistic basis for electromechanical coupling.

NCBE (SLC4A10) is important for cerebrospinal fluid pH regulation. Here, authors determine cryo-EM structures of human NCBE that reveal ion binding, inhibitor recognition, and the structural basis of substrate coupling in this transporter.

This study assesses the techno-economic and environmental performance of granular activated carbon and ion exchange resins across U.S. water utilities, identifying key cost and impact drivers to inform more sustainable and equitable PFAS treatment strategies.

Phosphorylation can alter the charge of intrinsically disordered proteins and thereby regulate their interactions. Here, the authors show that phosphorylation acts as an electrostatic rheostat for SRSF1- RNA binding, with binding free energy varying approximately linearly with net charge.

Extraction of lithium ions (Li⁺) from sea salt, minerals, and waste is important, but the availability of extraction methods that offer both high selectivity and strong lithium affinity is limited. Here, the authors report a dioxaborole-linked, head-to-tail assembled macrocycle – termed borphyrin – featuring a rigid cavity with a 16-crown-4-like configuration.

In this study, the authors show that post-treatment desethylamodiaquine concentration is the primary pharmacokinetic determinant of protection against malaria infection in African children who are given sulfadoxine-pyrimethamine and amodiaquine for seasonal malaria chemoprevention, with little apparent effect from sulfadoxine-pyrimethamine.

Neural mechanisms underlying emotional processing are not fully understood. Using intracranial recordings in humans, this study finds that transient amygdala beta bursts are associated with valence-dependent hippocampal neuronal activity, revealing temporally precise dynamics of emotional processing.

Oncogenic KRAS causes replication stress that threatens genome stability during cancer development. Here, the authors show that ATR-regulated PrimPol switches between fork slowing and repriming modes to help cells tolerate KRAS-induced replication stress while limiting error-prone DNA synthesis.

Two-dimensional ferroelectrics are often constrained by stringent structural requirements for intrinsic polarity. Sun et al. demonstrate that high-entropy engineering enables switchable polarization in centrosymmetric van der Waals materials, offering a potential pathway toward emergent ferroelectric-like states.