ClinVar's Data Model
Submitted records
ClinVar's data model is based on submitted data. At a minimum, each submission to ClinVar includes these fields:
- a variant description
- a condition the variant is classified for
- the classification of the variant for the condition
- at least one observation of the variant; observations may be
- an aggregation observation of more than one invidual with the variant
- a case-level observation
- an observation of the variant in a functional assay
A record is created for each submission to ClinVar. Each submitted record is assigned an accession number beginning with the prefix SCV.
Aggregate records
Submitted records are aggregated so that classifications and evidence can be viewed together. Submitted records are aggregated in two ways:
- aggregated by variant and assigned an accession number beginning with the prefix VCV
- aggregated by variant-condition and assigned an accession number beginning with the prefix RCV
Data model infographic
