Questions tagged [senescence]
The process of biological aging or the state of an organism being biologically old.
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Do trees have epigenetic clocks?
In humans epigenetic clocks have attained phenomenal performance when predicting chronological age.
There are questions about the source of trees used in for electricity generation, with claims that ...
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How many techniques are being developed/explored to stop, slow or reverse aging in humans?
I like reading science news and several times news about this have popped up. So far I've seen at least 3,
Japanese scientists discover protein aging
Japanese scientists have discovered several ...
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How many species of animals are biologically immortal?
Biological immortality describes the state where an organism does not age and its rate of mortality from senescence does not increase with chronological age. While biologically immortal beings can ...
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How old is this Kodiak bear?
Apologies if this is off-topic, I couldn't think of a more relevant SE site to post this.
Wikipedia has the following picture of a captive Kodiak bear in (presumably) a zoo in Germany. How old is this ...
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What's the centromere effect on aging?
How does centromere decay contribute to aging?
I am curious about their restoration in somatic and/or reproductive cells
There are also candidates for "centromerase" analog of telomerase:
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Why does increased age cause degradation?
(I'm not super familiar with biology just curious, so bear with me!)
My understanding:
As people get older (or are very unhealthy) they have accumulated more "bad habits" than others who are ...
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Why do old willows have so many broken limbs?
Willows have a reputation for being very flexible. In a nearby park (PA), where I often walk, there are about 20 willows growing by a stream. Willows over 30' to 40' tall have almost all their major ...
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What causes the activation of "Late acting deleterious genes" in late age but not in young age, whose accumulation causes ageing according to Medawar?
Sir Peter Medawar proposed that aging is the byproduct of "late acting deleterious genes". Evolution is good at weeding out genetic mutations that are harmful at an young age, before the ...
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Does Dr. Sinclair's Epigenome Resetting in ICE Mice Also Repair Telomere Length?"
Dr. Sinclair's team at Harvard University has published a paper this year on rejuvenating ICE mice by reprogramming cells to reset the epigenome. Does this cellular reprogramming also repair the ...
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Is there a link between SASP and fibrosis?
1/ Fibrosis: Fibrosis is the formation of excessive fibrous connective tissue in an organ or tissue during a reparative process.
2/ SASP: SASP is the accumulation of molecules and senescent cells in ...
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Variance in epigenetic drift rate between different species
My question relates to the prospect of (near?) future control of biological aging.
As I understand, it has been recently demonstrated by Prof. David Sinclair's group that epigenetic drift appears to ...
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Does your body type affect the rate at which you age
Out of the 3 body types: ectomorph, endomorph and mesomorph, does one age quicker/slower than the others or does it not matter so much?
There are many factors that affect the rate of ageing, but I'm ...
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In life history theory, does trade-off between reproduction and growth and maintenance imply longer health span for a sexually inactive organism?
The life history theory suggests that there exists trade-off between life processes like reproduction and growth and maintenance of the organism.
One significant trade off is between somatic effort (...
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difference between proximal and distal mechanisms of aging in biogerontology?
In his book Biology of Aging, Roger McDonald describes the difference between causes and mechanisms of aging; and states that the cause of aging is essentially thermodynamic (entropy) and that ...
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Evolution of Aging according to Weismann
Several authors agree to the fact that August Weismann was the first to propose an explanation to biological aging (Kirkwood and Cremer, 1982; Gems and Partridge, 2013).
A lot of hallmarks (and some ...
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