Role of Maternal Dietary Peanut Exposure in Development of Food Allergy and Oral Tolerance
Fig 7
OVA epicutaneous sensitization after feeding OVA with or without murine milk.
(A) Experimental protocol. Offspring come from naïve mothers. Offspring’s response to OVA challenge (B-C) and antibody responses to OVA sensitization (D-F). Mice post-weaning at 3–4 weeks of age were fed OVA +/- OVA-immune or naïve milk for 5 days followed by cutaneous sensitization with OVA. Mice immunized without prior OVA feeding (Unfed) were used as controls. X axis for D-F shows the dilution factor for the serum. Each group has 5 mice. Shown is a mean with SEM. **, p<0.01, ***, p<0.001, ****, p<0.00001 when compared to unfed.
