Welcome to the Biohub Platform
Build on the world model of protein biology.
ESMFold2
A state-of-the-art model for biomolecular complex structure prediction.
ESMC
A state-of-the-art protein language model powering functional analysis, structure prediction, and protein design.
ESM Atlas
An open database of functional annotations for over 6.8 billion proteins and 1.1 billion paired high-resolution predicted structures.
Models
Explore the ESM family of models through Biohub's open platform.
ESMC
ESMC builds representations that capture the fundamental mechanisms of protein structure and function from billions of evolutionary sequences.
Discover ESMCESMFold2
ESMFold2 predicts high-resolution, all-atom 3D structures of biomolecular complexes directly from sequences, with optional multiple sequence alignment (MSA) input for enhanced accuracy on challenging targets.
Discover ESMFold2ESM3
ESM3 jointly models sequence, structure, and function. It enables controllable generation of novel proteins by conditioning on any combination of these modalities.
Discover ESM3Tools
Predict protein structures and explore relationships across proteins through interactive web-based tools — all powered by the ESM family of models.
ESM Atlas
Explore billions of proteins across all life on Earth using sequence search or natural language to discover structural and functional relationships between proteins.
Explore the AtlasFold
Predict 3D structures of biomolecular complexes directly from protein, DNA, and RNA sequences.
Explore FoldDeveloper Resources
Learn how to use the Biohub Platform's open API.