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@ShenLab

Shen Lab at Columbia University

Computational genomics, human genetics, and computational immunology

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  1. SeqDance SeqDance Public

    code for SeqDance/ESMDance, biophysics-informed protein language models

    Jupyter Notebook 65 6

  2. gMVP gMVP Public

    Python 21 7

  3. missense missense Public

    MVP (Qi et al 2021) source code

    Jupyter Notebook 18 9

  4. CANOES CANOES Public

    R 9 2

  5. ThreaderAI ThreaderAI Public

    Template-based prediction of protein structure with deep-learning

    C++ 7 2

  6. PreModeArchive PreModeArchive Public

    PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context

    Python 7 1

Repositories

Showing 10 of 52 repositories
  • EATEF2026 Public
    ShenLab/EATEF2026's past year of commit activity
    Python 0 MIT 0 0 0 Updated Sep 21, 2026
  • shenlab.github.io Public

    large files (PDF or images) for Shen Lab

    ShenLab/shenlab.github.io's past year of commit activity
    0 0 0 0 Updated Sep 3, 2026
  • Genetics Public
    ShenLab/Genetics's past year of commit activity
    Python 1 4 0 2 Updated Jul 22, 2026
  • MisFit Public

    Estimation of selection coefficient of missense variants using human population genomes and machine learning

    ShenLab/MisFit's past year of commit activity
    Python 6 1 0 0 Updated May 8, 2026
  • MDmis Public

    Molecular dynamics simulations for missense variants in intrinsically disordered protein regions

    ShenLab/MDmis's past year of commit activity
    Jupyter Notebook 1 0 0 0 Updated Feb 24, 2026
  • SPARK3 Public

    scripts used in autism exome data analysis in Qiao et al 2026

    ShenLab/SPARK3's past year of commit activity
    R 0 MIT 0 0 0 Updated Feb 20, 2026
  • SeqDance Public

    code for SeqDance/ESMDance, biophysics-informed protein language models

    ShenLab/SeqDance's past year of commit activity
    Jupyter Notebook 65 GPL-3.0 6 3 0 Updated Jan 28, 2026
  • kif1a Public
    ShenLab/kif1a's past year of commit activity
    Ruby 0 MIT 1 0 0 Updated Oct 2, 2025
  • mutable-sh Public
    ShenLab/mutable-sh's past year of commit activity
    HTML 0 0 0 0 Updated Jul 31, 2025
  • PreMode Public
    ShenLab/PreMode's past year of commit activity
    Python 5 0 0 0 Updated Jul 7, 2025

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