Assistant Professor | Computational Immunologist | Tool Builder
Washington University · Department of Pathology & Immunology
I work at the intersection of computational biology and immunology, developing tools and methods to decode immune responses from high-dimensional data.
- MD/PhD — University of Iowa (Medical Scientist Training Program)
- Residency & Postdoc — Washington University PSTP (co-mentored by Jon Brestoff & David DeNardo)
- Fellowship - Histocompatibility and Immunogenetics
- Focus — Innate cellular barcodes (mitochondrial genomes, immune receptor sequences) for tracking immune responses and predicting clinical outcomes
I build R/Bioconductor packages for single-cell immune analysis:
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scRepertoire TCR/BCR repertoire analysis 
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escape Gene set enrichment 
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Trex TCR deep learning 
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Ibex BCR deep learning 
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immApex Immune receptor featurization
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In development: immReferent · immLynx · immGLIPH · deepMatchR · bHIVE
- Bug reports or feature requests? Open an issue on the relevant repo
- Collaboration inquiries? Reach out via my website
- Publications? PDFs available at borch.dev
Building tools to decode the immune system 🧬
