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Read-ahead / write-behind byte IO: threaded Reader/Writer that decouple a pipeline stage from the kernel pipe via a background thread and a byte ring buffer

Rust 4 Updated Sep 20, 2026

Deciphering spatial ecotypes from spatial, single-cell, and bulk transcriptomic data

R 49 4 Updated Sep 25, 2026

Cargo subcommand to build multiple versions of the same binary, each with a different CPU features set, merged into a single portable optimized binary

Rust 241 10 Updated Jul 4, 2026

Fast, highly accurate, read-trimming for NGS data.

Rust 24 Updated Oct 1, 2026

A crate to help you go wide. By which I mean use SIMD stuff.

Rust 557 60 Updated Sep 23, 2026

A zlib implementation in rust available as a C dynamic library and as a rust crate

Rust 697 60 Updated Sep 17, 2026

Tools (written in C using htslib) for manipulating next-generation sequencing data

C 1,964 619 Updated Oct 1, 2026

Low Coverage Calling of Genotypes

C++ 181 42 Updated Sep 13, 2026

NGS read simulator

Rust 6 Updated Oct 2, 2026

Bioinformatics I/O libraries in Rust

Rust 727 86 Updated Oct 1, 2026

Spiritual successor to picard for sequencing qc

Rust 63 4 Updated Oct 2, 2026

Heavily optimized library for DEFLATE/zlib/gzip compression and decompression

C 1,295 219 Updated Aug 22, 2026

Java JNI wrapper around libdeflate for faster DEFLATE/gzip/zip on the JVM

Java 6 Updated Aug 24, 2026

A scientific plotting library in Rust

Rust 875 40 Updated Sep 24, 2026

A high-performance HGVS variant nomenclature parser and normalizer written in Rust

Rust 30 4 Updated Sep 26, 2026

Fast FASTQ sample demultiplexing in Rust.

Rust 71 2 Updated Sep 26, 2026

A better, faster way to count guides in CRISPR screens.

Rust 35 4 Updated Apr 30, 2026

A small utility for formatting things the way Tim prefers.

Rust 4 Updated Sep 3, 2021

Data from the Human PanGenomics Project

61 4 Updated Jul 15, 2021

CellBender is a software package for eliminating technical artifacts from high-throughput single-cell RNA sequencing (scRNA-seq) data.

Python 423 92 Updated Sep 12, 2026

This repository contains information about latest release from Genome in a Bottle project

75 5 Updated Aug 30, 2019

An argument parsing library for Scala

Scala 12 Updated May 19, 2026

Common scala utilities

Scala 5 3 Updated Mar 28, 2026

Create force-directed graphs of RNA secondary structures.

JavaScript 115 34 Updated Jun 6, 2020

Java Bindings (JNI) for bwa

Java 22 11 Updated Dec 15, 2016

Tools for working with genomic and high throughput sequencing data.

Scala 373 79 Updated Aug 20, 2026

A scala based DSL and framework for writing and executing bioinformatics pipelines as Directed Acyclic GRaphs

Scala 70 13 Updated May 27, 2022

A Java API for high-throughput sequencing data (HTS) formats.

Java 303 243 Updated Oct 2, 2026

A set of command line tools (in Java) for manipulating high-throughput sequencing (HTS) data and formats such as SAM/BAM/CRAM and VCF.

Java 1,080 384 Updated Jul 31, 2026