MA46204A - CRYSTALLINE FORMS OF LYSYL OXIDASE TYPE 2 INHIBITOR AND METHODS FOR MANUFACTURING THEM - Google Patents

CRYSTALLINE FORMS OF LYSYL OXIDASE TYPE 2 INHIBITOR AND METHODS FOR MANUFACTURING THEM

Info

Publication number
MA46204A
MA46204A MA046204A MA46204A MA46204A MA 46204 A MA46204 A MA 46204A MA 046204 A MA046204 A MA 046204A MA 46204 A MA46204 A MA 46204A MA 46204 A MA46204 A MA 46204A
Authority
MA
Morocco
Prior art keywords
inhibitor
manufacturing
methods
crystalline forms
lysyl oxidase
Prior art date
Application number
MA046204A
Other languages
French (fr)
Inventor
Kevin Ross Holme
David Lonergan
Martin W Rowbottom
Original Assignee
Pharmakea Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmakea Inc filed Critical Pharmakea Inc
Publication of MA46204A publication Critical patent/MA46204A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66—Methanesulfonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA046204A 2016-09-07 2017-09-06 CRYSTALLINE FORMS OF LYSYL OXIDASE TYPE 2 INHIBITOR AND METHODS FOR MANUFACTURING THEM MA46204A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662384596P 2016-09-07 2016-09-07

Publications (1)

Publication Number Publication Date
MA46204A true MA46204A (en) 2021-03-17

Family

ID=61561660

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046204A MA46204A (en) 2016-09-07 2017-09-06 CRYSTALLINE FORMS OF LYSYL OXIDASE TYPE 2 INHIBITOR AND METHODS FOR MANUFACTURING THEM

Country Status (14)

Country Link
US (2) US10774069B2 (en)
EP (1) EP3510023B1 (en)
JP (1) JP7079772B2 (en)
KR (1) KR102587178B1 (en)
CN (1) CN109983006B (en)
AU (1) AU2017324445A1 (en)
BR (1) BR112019004517A2 (en)
CA (1) CA3036064A1 (en)
EA (1) EA201990621A1 (en)
IL (1) IL265192A (en)
MA (1) MA46204A (en)
MX (1) MX390964B (en)
SG (1) SG11201901999XA (en)
WO (1) WO2018048943A1 (en)

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WO2016144703A1 (en) 2015-03-06 2016-09-15 Pharmakea, Inc. Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof
CN108884049A (en) * 2016-02-09 2018-11-23 法玛克亚公司 2 inhibitor of quinolinone lysyloxidase sample and application thereof
MX2019002612A (en) 2016-09-07 2019-08-21 Pharmakea Inc Uses of a lysyl oxidase-like 2 inhibitor.
MX390964B (en) * 2016-09-07 2025-03-21 Pharmakea Inc CRYSTALLINE FORMS OF A LYSYL OXIDASE 2 TYPE INHIBITOR AND METHODS OF PREPARATION.
GB201716871D0 (en) 2017-10-13 2017-11-29 Inst Of Cancer Research: Royal Cancer Hospital Compounds
CN114487139B (en) * 2020-10-27 2025-01-14 鲁南制药集团股份有限公司 A method for detecting related substances of cetirizine hydrochloride

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Also Published As

Publication number Publication date
JP7079772B2 (en) 2022-06-02
CN109983006A (en) 2019-07-05
CN109983006B (en) 2022-02-25
US20190202805A1 (en) 2019-07-04
EA201990621A1 (en) 2019-09-30
AU2017324445A1 (en) 2019-04-11
MX2019002615A (en) 2019-10-15
US11459309B2 (en) 2022-10-04
JP2019532919A (en) 2019-11-14
IL265192A (en) 2019-05-30
SG11201901999XA (en) 2019-04-29
US10774069B2 (en) 2020-09-15
KR102587178B1 (en) 2023-10-06
BR112019004517A2 (en) 2019-08-13
WO2018048943A1 (en) 2018-03-15
EP3510023B1 (en) 2024-06-19
EP3510023A1 (en) 2019-07-17
CA3036064A1 (en) 2018-03-15
EP3510023A4 (en) 2020-03-18
KR20190052040A (en) 2019-05-15
MX390964B (en) 2025-03-21
US20200361901A1 (en) 2020-11-19

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