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Human BioMolecular Atlas Program (HuBMAP)
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@_hubmap

Human BioMolecular Atlas Program (HuBMAP)

@_hubmap
an NIH-funded consortium of scientists developing an open, global framework for comprehensively mapping the human body at a cellular resolution.
hubmapconsortium.org
Joined March 2019
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  • @_hubmap
    Human BioMolecular Atlas Program (HuBMAP)
    @_hubmap
    Aug 14
    I spleen, you spleen, we all spleen for this spleen-did Xenium image of a human spleen, the organ that filters blood, produces immune cells, and helps your body fight infections made by HuBMAP researchers Drs. Gloria Pryhuber (URMC) and Chenchen Zhu (Stanford).
    Xenium technology shows researchers where specific RNAs reside in an organ, giving them an idea about how the RNAs relate to each other in the space of the organ. It’s spleen-tastic!

White – mesenchymal cells, green – endothelial cells, magenta – myeloid cells, blue – neurons, yellow – muscle cells, red – epithelial, teal – lymphoid, gray – other
    2
  • @_hubmap
    Human BioMolecular Atlas Program (HuBMAP)
    @_hubmap
    Jul 27
    The pandemonium of daily life has you insulinely tired? Then pan a shot over to this Xenium image of the thousands of RNAs that reside within the body of the pancreas, made by HuBMAP researcher Chenchen Zhu from @Stanford, who is nothing if not pancreas-ionate about his work!
    Xenium image of the thousands of RNAs that reside within the body of the pancreas

White - mesenchymal cells, green - endothelial cells, magenta- myeloid, blue - nerve cells, yellow - muscle, red - epithelial, teal - lymphoid cells, gray - other
    1
  • @_hubmap
    Human BioMolecular Atlas Program (HuBMAP)
    @_hubmap
    May 19
    Once again, the certified #_HuBMAP air-tists/researchers in Dr. Gloria Pryhuber's lab at @UR_Med hope to take your breath away with this multimodal image of airway epithelium, submucosal gland, and duct from the lung. We hope it respires you to live lung and prosper.
    Multimodal image of airway epithelium, submucosal gland, and duct from the lung.

Lung - Airway Epithelium and Submucosal Gland and Duct
PTPRC - CD45 - Orange - immune cells
PECAM1 - CD31 - Green - endothelial cells
KRT5 - Yellow - basal epithelial cells
ACTA2 - White - smooth muscle cells
FOXJ1 - orange in epithelium, motile ciliated cells
SCGB3A2 - pink - lung epithelial cells and submucosal glands
SFTPB - pulmonary surfactant protein
MUC5AC - bright blue - gel-forming glycoprotein in the lungs
MUC5B - turquoise - gel-forming mucin protein
    1
  • @_hubmap
    Human BioMolecular Atlas Program (HuBMAP)
    @_hubmap
    May 5
    Does this CODEX image of an ovary send you ova the moon? This egg-citing image was made by NIH funded #_HuBMAP scientists @upenn & @LurieChildren's, using antibodies specific to cell types found in the ovary to show the spatial relationships within. Ova it? Never!!!!
    CODEX image of an ovary

follicles - red and blue, luteinizing cells - pink, extracellular matrix - purple, green, white, vessels - yellow and orange
    1
  • @_hubmap
    Human BioMolecular Atlas Program (HuBMAP)
    @_hubmap
    Apr 15
    Not to be an ovary-achiever, but this CODEX image of oocytes in a healthy human ovary made by scientists at @UPenn & @LurieChildren’s is egg-straordinary! Images like this prove researchers aren’t just follicle-ing around! 😉
    CODEX image of oocytes in a healthy human ovary.
 
Green – oocytes, Pink – extracellular matrix, Cyan – vessels, Blue and Yellow – epithelial cells
 
Photo credit - UPenn & Lurie Children’s (O’Neill, Kim, Laronda)
    2