American Cancer Society Research

𝗔𝗖𝗦 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻 𝘁𝗵𝗲 𝗻𝗲𝘄𝘀! Earlier today, Dr. Alpa Patel, Senior Vice President for Population Science, made an appearance on 𝘎𝘰𝘰𝘥 𝘔𝘰𝘳𝘯𝘪𝘯𝘨 𝘈𝘮𝘦𝘳𝘪𝘤𝘢 to kick off #BreastCancerAwarenessMonth. Dr. Patel shared important findings from a recent survey of 33,000 participants enrolled in our ongoing Cancer Prevention Study-3, which uncovered significant gaps between what women know about cancer risk and the healthy behaviors that can help reduce it. 🔗 Read the full survey report here: https://lnkd.in/eHuVKddz The survey highlights substantial opportunities to improve awareness of modifiable risk factors for breast cancer and to encourage women to make informed choices that can lower their risk. These findings can strengthen public health awareness efforts as well as guide conversations between healthcare providers and their patients. The survey results also highlight the importance of initiatives to expand access to safe, walkable communities and affordable, healthy food. To watch the full interview with Dr. Patel, please visit https://lnkd.in/eNsTTfMy. #BCAM #CancerRisk #CPS3 #PopulationScience

🚨𝗪𝗲𝗯𝗶𝗻𝗮𝗿 𝗥𝗲𝗺𝗶𝗻𝗱𝗲𝗿 - 𝗧𝗢𝗗𝗔𝗬! 🚨 This afternoon, we will host our final Grant Opportunities Webinar for our current grant application cycle. Please join us from 4-5pm ET today to learn about our current grant funding opportunities and to hear guidance for funding success from Dr. Melissa Cunningham, Senior Science Director at American Cancer Society. 🔗 Register in advance here: https://lnkd.in/eWhgUwxc This webinar is intended for individuals at institutions in the North Region, but is open to anyone who is interested in applying that has not attended one of our previous webinars this cycle. See you there!

It's time for this week's #ACSFriday5, where we highlight five recent publications from our ACS researchers. Here are this week's top picks: 1. A new paper in The Journal of Clinical Investigation family of journals from ACs postdoctoral fellow Dr. Tianli X. at Yale University that identified a unique mechanism of disease in human DPP9 deficiency, which causes pancytopenia through CARD8-mediated pyroptosis in hematopoietic stem and progenitor cells. Senior author Dr. Diane Krause is also a past ACS grantee. 🔗 Read the full paper at https://lnkd.in/e4G7fBbf 2. New research in 𝘊𝘢𝘯𝘤𝘦𝘳 𝘌𝘱𝘪𝘥𝘦𝘮𝘪𝘰𝘭𝘰𝘨𝘺 𝘉𝘪𝘰𝘮𝘢𝘳𝘬𝘦𝘳𝘴 & 𝘗𝘳𝘦𝘷𝘦𝘯𝘵𝘪𝘰𝘯 from lead author Dr. Qinjin Fan and our intramural cancer surveillance team that found Increased broadband access, combined with telehealth waivers during the pandemic may have supported greater access to and continuity of high-quality cancer care, particularly among patients in non-metropolitan areas. ACS co-authors on the paper include Margaret Katana Ogongo, Leticia Nogueira, Xuesong Han, senior author Robin Yabroff, PhD, MBA, FASCO, and ACS grantee/visiting scientist Xin (Cynthia) Hu. 🔗Read the full paper at https://lnkd.in/e6zECPHD 3. A new publication in Trends in Biotechnology from senior author Dr. Gautam Dantas and his team at Washington University in St. Louis describing their development of a 125-plex secretion construct library for the probiotic yeast Saccharomyces cerevisiae var. boulardii, enabling over 1800-fold variation in protein expression. ACS supported this work through Dr. Dantas' ACS-Yosemite grant. 🔗 Read the full paper here: https://lnkd.in/eizmDz6C 4. A new paper in 𝘔𝘰𝘭𝘦𝘤𝘶𝘭𝘢𝘳 𝘛𝘩𝘦𝘳𝘢𝘱𝘺 from senior author Dr. Ji Young Yoo and their team at UTHealth Houston describing their work on therapy-induced IGF1R signaling as an actionable vulnerability in oncolytic virotherapy. ACS supported this work through Dr. Yoo's Research Scholar Grant. 🔗 Read the full paper here: https://lnkd.in/eW2H27tA 5. A new review in 𝘙𝘢𝘥𝘪𝘰𝘭𝘰𝘨𝘺 from lead author Dr. Rony Avritscher at the The University of Texas MD Anderson Cancer Center discussing the integration of yttrium 90 (90Y) radioembolization with immunotherapy for advanced-stage hepatocellular carcinoma (HCC), highlighting its potential to enhance treatment efficacy despite existing resistance mechanisms. Dr. Avritscher is an ACS Research Scholar grantee. Past ACS grantee Dr. Terence Gade is a co-author on the review. 🔗 Read the full paper here: https://lnkd.in/ebPA39U8 Congratulations to everyone on these great accomplishments!

On this World Cancer Research Day, we thank you for helping us to support cancer researchers doing important work across the cancer research spectrum. And to our researchers, thank you for your passion and commitment to helping us end cancer as we know it, for everyone. #WorldCancerResearchDay

🚨 𝗪𝗲𝗯𝗶𝗻𝗮𝗿𝘀 𝗥𝗲𝗺𝗶𝗻𝗱𝗲𝗿! 🚨 We will be hosting three webinars this week to share information about our current grant funding opportunities with interested potential applicants. If you are a cancer researcher looking for funding, please join us for one of the following webinars: 𝘞𝘦𝘣𝘪𝘯𝘢𝘳 1: 𝘞𝘦𝘴𝘵 𝘙𝘦𝘨𝘪𝘰𝘯 - Tuesday, September 22 from 4-5pm EDT - Register at https://lnkd.in/eKk3N8rG 𝘞𝘦𝘣𝘪𝘯𝘢𝘳 2: 𝘕𝘰𝘳𝘵𝘩𝘦𝘢𝘴𝘵 𝘙𝘦𝘨𝘪𝘰𝘯 - Wednesday, September 23 from 11am-12:30pm EDT - Register at https://lnkd.in/eKFC_DR4 𝘞𝘦𝘣𝘪𝘯𝘢𝘳 3: 𝘚𝘰𝘶𝘵𝘩 𝘙𝘦𝘨𝘪𝘰𝘯 - Thursday, September 24 from - Register at https://lnkd.in/eXb_QD2P To see the full list of upcoming webinars, please visit https://lnkd.in/eVkGXfHF. To learn more about our current grant opportunities, visit https://lnkd.in/ey2aHEGf. #CancerResearch #GrantOpportunities #FundingOpportunities #FundingWebinars

*slams the laptop shut until Monday* . . . *reopens laptop* Wait! We can't sign off for the weekend until we post this week's #ACSFriday5, our weekly spotlight post featuring five new publications from our ACS researchers! Without further ado, here are this week's new papers: 1. A new publication in Cell Metabolism by Cell Press from senior author (and ACS Professor) Dr. Yibin Kang at Princeton University identifying host metadherin (MTDH) as a critical regulator of tumor-induced immunosuppression and metabolic reprogramming via tumor-liver interactions. ACS Research Scholar grantee Dr. Liling Wan is a co-author on the paper. 🔗Read the full paper here: https://lnkd.in/eKRKSWA9 2. New research in 𝘊𝘢𝘯𝘤𝘦𝘳 (American Cancer Society Journals) from our intramural cancer surveillance team that concluded that addressing barriers for individuals with self-care limitations could improve suboptimal screening levels across multiple cancer screenings. Natalia Mazzitelli, MPH was the lead author on the study. Additional ACS co-authors include Jessica Star, MA, MPH, Dr. Xuesong Han, and senior author Dr. Priti Bandi. 🔗Read the full paper here: https://lnkd.in/eBaMNBRR 3. A new paper in 𝘔𝘰𝘭𝘦𝘤𝘶𝘭𝘢𝘳 𝘊𝘦𝘭𝘭 from senior author Dr. Alexander Ruthenburg at the University of Chicago that demonstrated that WDR5 (an essential subunit of the MLL1/KMT2A histone methyltransferase complex) directly engages a diverse pool of cellular RNAs, dictated primarily by RNA abundance rather than specific motifs. ACS supported this work through Dr. Ruthenburg's recent Research Scholar Grant. 🔗Read the full paper here: https://lnkd.in/ed5UiY7R 4. New research published in 𝘕𝘢𝘵𝘶𝘳𝘦 𝘉𝘪𝘰𝘵𝘦𝘤𝘩𝘯𝘰𝘭𝘰𝘨𝘺 from senior author Dr. Quanyin Hu at the University of Wisconsin-Madison that introduced macropinocytosis-mediated recyclable LYTACs (McR-TACs) and demonstrated that these chimeras effectively degrade cell membrane and extracellular proteins, demonstrating potential in inhibiting tumor growth in a triple-negative breast cancer mouse model. Dr. Hu is a current ACS Research Scholar grantee. 🔗Read the full paper here: https://lnkd.in/eEjEqQwT 5. Finally, new results from the IGNITE-TX Pilot Randomized Clinical Trial published in JAMA Network Open that showed that participants utilizing IGNITE-TX (a bilingual, navigator-supported digital intervention to increase genetic testing) had significantly higher cascade genetic testing completion rates, improved informed decision-making, and greater readiness to pursue testing compared to those in non-IGNITE-TX arms. ACS supported this trial through senior author Dr. J. Alejandro Rauh-Hain's current Discovery Boost Grant. 🔗Read the full paper here: https://lnkd.in/e8Udvj4J Congratulations to everyone on these great accomplishments!

What a day at the American Cancer Society Center for Innovation in Cancer Research Training Annual Meeting! The morning kicked off bright and early with scientific talks from selected postbaccalaureate fellows. Afterwards, program managers and PIs transitioned to an annual business meeting where they shared insights from across their programs while the fellows participated in career building sessions including guidance for applying to graduate and medical schools, resume reviews, and even mock interviews. A highlight of the afternoon was the roundtable discussions where fellows could pick the brains of veteran cancer researchers. Finally, the day wrapped up with awards presented for best talks and posters during the meeting and some insightful reflections from the fellows. With networking opportunities throughout our time together in Atlanta, the meeting was full of encouragement, enthusiasm, and excitement for the future of cancer research! Special thank you to our platinum sponsor for this meeting Actalent who helped bring to life our career development sessions and shared practical guidance with participants throughout the meeting. To our graduating fellows, we can't to see what you do next, and to everyone else - we'll see you again next year! #CancerResearchTraining #ResearchTraining #Mentorship #PostBacc Elvan Daniels Chanda Felton, MPH Dani Morrow (Smith), MPH, MCHES®

One of the cornerstones of our 𝗖𝗲𝗻𝘁𝗲𝗿 𝗳𝗼𝗿 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 𝗖𝗮𝗻𝗰𝗲𝗿 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗧𝗿𝗮𝗶𝗻𝗶𝗻𝗴 (𝗖𝗜𝗖𝗥𝗧) 𝗣𝗼𝘀𝘁-𝗕𝗮𝗰𝗰𝗮𝗹𝗮𝘂𝗿𝗲𝗮𝘁𝗲 𝗽𝗿𝗼𝗴𝗿𝗮𝗺 is the opportunity for fellows to complete two years of hands-on cancer research, training in a lab alongside experienced mentors. During Day 1 of this week's CICRT Annual Meeting in Atlanta, many of our post bacc fellows presented posters of their research to their peers, program mentors, and other meeting participants from the American Cancer Society and beyond. With projects ranging from basic and translational research to behavioral inventions, epidemiology, and beyond, our fellows demonstrated their growing expertise, their thoughtfulness, and their passion for helping to end cancer as we know it, for everyone. 🔗 Learn more about the CICRT Post Bacc program: https://lnkd.in/exKUNSg3 During Day 2, we will hear talks from more of our fellows before transitioning into a series of career development workshops presented with support from our platinum meeting sponsor Actalent. Stay tuned for more highlights from this engaging meeting! #CancerResearchTraining #CancerResearch #ResearchTraining #PostBacc Elvan Daniels Dani Morrow (Smith), MPH, MCHES® Chanda Felton, MPH

We are thrilled to welcome our funded fellows and program leaders from our 𝗖𝗲𝗻𝘁𝗲𝗿 𝗳𝗼𝗿 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 𝗖𝗮𝗻𝗰𝗲𝗿 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗧𝗿𝗮𝗶𝗻𝗶𝗻𝗴 for the 2026 annual meeting! We kicked things off earlier today with a warm welcome from Senior Vice President of CICRT, Dr. Elvan Daniels and an inspiring keynote address from Dr. Carmen Guerra from the University of Pennsylvania. Over the remainder of the next two days, our Fellows will have the opportunity to share their research, participate in career development sessions, and network with leaders in cancer research as part of their ongoing training. It promises to be an encouraging and thought-provoking meeting for everyone involved! 🔗 Learn more about the Center for Innovation in Cancer Research Training here: https://lnkd.in/eNXbgiwg 𝘚𝘱𝘦𝘤𝘪𝘢𝘭 𝘵𝘩𝘢𝘯𝘬𝘴 𝘵𝘰 𝘰𝘶𝘳 𝘗𝘭𝘢𝘵𝘪𝘯𝘶𝘮 𝘚𝘱𝘰𝘯𝘴𝘰𝘳 Actalent 𝘧𝘰𝘳 𝘩𝘦𝘭𝘱𝘪𝘯𝘨 𝘶𝘴 𝘱𝘳𝘰𝘷𝘪𝘥𝘦 𝘵𝘩𝘪𝘴 𝘰𝘱𝘱𝘰𝘳𝘵𝘶𝘯𝘪𝘵𝘺 𝘧𝘰𝘳 𝘰𝘶𝘳 𝘊𝘐𝘊𝘙𝘛 𝘍𝘦𝘭𝘭𝘰𝘸𝘴 𝘢𝘯𝘥 𝘱𝘳𝘰𝘨𝘳𝘢𝘮 𝘭𝘦𝘢𝘥𝘦𝘳𝘴.