Cell Discovery

Cell signaling and transcriptional regulation of osteoclast lineage commitment, differentiation, bone resorption and diseases

Siyu Zhu
Ming-Qi Yan
Yi-Ping Li

Review Article 20 January 2026

Featured

Bilirubin directly activates RIPK3 to induce non-classical necroptosis

Qian Xue
Xi Ma
Jinbao Liu
ArticleOpen Access24 Mar 2026
Inosine promotes erythrocyte metabolic reprogramming and restores oxygen release for rejuvenation via 2,3-BPG-PNP axis

Wuping Liu
Zhaoyu Yang
Yang Xia
ArticleOpen Access17 Mar 2026
Chronobiology of neurotropic viruses: rhythmic viral entry and arrhythmic host clocks

Shaowei Zeng
Qian Zhang
Bishi Fu
ArticleOpen Access10 Feb 2026
Integrating single-nucleus barcoding with spatial transcriptomics via Stamp-seq to reveal immunotherapy response-enhancing functional modules in NSCLC

Yitong Pan
Huan Yan
Chenxi Tian
ArticleOpen Access05 Feb 2026

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Editorial Excellence

Cell Discovery, among the top 15% qualifying journals, is recognized for its exceptional editorial excellence, based on data collected from the 2024 Journal Author Satisfaction survey. Congratulations to the Cell Discovery editors!
Meet us at annual meeting of CSCB

Have questions about our journals? Stop by to chat with our editors about submissions, editorial expectations, and peer review. Join us for a chance to receive a Springer Nature gift. | Journals: Cell Research, Cell Discovery | Editors: Lei Cheng, Wencong Lyu | Time: 15:15 – 16:15, April 10 | Location: Booth 96, Annual Meeting of Chinese Society for Cell Biology, Anhui Province, China
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In these Behind the Paper posts, our authors share the real stories behind the latest research papers, from conception to publication, the highs and the lows.

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Loss-of-function variants in ODAD1 disrupt ODA docking and induce actin cytoskeletal remodeling in primary ciliary dyskinesia

Chunxiao Huo
Ting Luo
Shanshan Xie
ArticleOpen Access31 Mar 2026
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction

Yi-yang Zhao
Yi-hui Wang
Min Chen
ArticleOpen Access31 Mar 2026
Structural basis of human zinc-activated channel (ZAC) signaling and modulation

Zixuan Zhou
Yonghui Long
Qianhui Qu
ArticleOpen Access31 Mar 2026
Highly regional generation and heterogeneous differentiation of basal cells in mouse trachea

Xiuxiu Liu
Wendong Weng
Bin Zhou
CorrespondenceOpen Access30 Mar 2026
Sheep blastocyst-like structure models derived from stem cells

Jing Cao
Jie Li
Xiaolong Wang
CorrespondenceOpen Access24 Mar 2026
Bilirubin directly activates RIPK3 to induce non-classical necroptosis

Qian Xue
Xi Ma
Jinbao Liu
ArticleOpen Access24 Mar 2026
Rapid production of precisely edited cattle and mice via a single AAV delivered miniature IscB^#/ωRNA^#

Lishuang Song
Xuefei Liu
Lei Yang
CorrespondenceOpen Access17 Mar 2026
Inosine promotes erythrocyte metabolic reprogramming and restores oxygen release for rejuvenation via 2,3-BPG-PNP axis

Wuping Liu
Zhaoyu Yang
Yang Xia
ArticleOpen Access17 Mar 2026
The mitochondrial translocation of phosphorylated EZH2 promotes PARP inhibitor resistance in BRCA1-deficient epithelial ovarian cancer

Ling Hu
Xiaolu Ma
Renquan Lu
ArticleOpen Access12 Mar 2026

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Editor’s selections: top articles from the past 3 years

Cell Discovery is proud to present a collection of featured articles from the last 3 years that represent a broad scope in basic molecular and cell biology research.

Collection 21 Jun 2024

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This journal is a member of and subscribes to the principles of the Committee on Publication Ethics.

Cell signaling and transcriptional regulation of osteoclast lineage commitment, differentiation, bone resorption and diseases

Featured

Bilirubin directly activates RIPK3 to induce non-classical necroptosis

Inosine promotes erythrocyte metabolic reprogramming and restores oxygen release for rejuvenation via 2,3-BPG-PNP axis

Chronobiology of neurotropic viruses: rhythmic viral entry and arrhythmic host clocks

Integrating single-nucleus barcoding with spatial transcriptomics via Stamp-seq to reveal immunotherapy response-enhancing functional modules in NSCLC

Announcements

Editorial Excellence

Meet us at annual meeting of CSCB

Behind the Paper

Browse articles

Loss-of-function variants in ODAD1 disrupt ODA docking and induce actin cytoskeletal remodeling in primary ciliary dyskinesia

Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction

Structural basis of human zinc-activated channel (ZAC) signaling and modulation

Highly regional generation and heterogeneous differentiation of basal cells in mouse trachea

Sheep blastocyst-like structure models derived from stem cells

Bilirubin directly activates RIPK3 to induce non-classical necroptosis

Rapid production of precisely edited cattle and mice via a single AAV delivered miniature IscB^#/ωRNA^#

Inosine promotes erythrocyte metabolic reprogramming and restores oxygen release for rejuvenation via 2,3-BPG-PNP axis

The mitochondrial translocation of phosphorylated EZH2 promotes PARP inhibitor resistance in BRCA1-deficient epithelial ovarian cancer

Collections

Editor’s selections: top articles from the past 3 years

Trending - Altmetric

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Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccines

Dysregulated hematopoiesis in bone marrow marks severe COVID-19

Prefrontal cortex-to-hypothalamic outputs orchestrate cue-potentiated palatable food consumption via AMPKβ2 signaling

Structural basis of human zinc-activated channel (ZAC) signaling and modulation

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