npj Parkinson's Disease

Neuromelanin imaging outperforms free water imaging in diagnosing early Parkinson’s disease: a comparative MRI study

Yun Hwa Roh
Jinyoung Youn
Beomseok Sohn

Article 13 February 2026

Featured

Detection of alpha-synuclein seeding activity in tear fluid in patients with Parkinson’s disease

Sezgi Canaslan
Matthias Schmitz
Inga Zerr
Brief CommunicationOpen Access18 Feb 2026
Testing an inverse link between limbic alpha-synucleinopathy and myelin markers in mice and humans

Rachel N. Clark
Reese E. Landes
Rehana K. Leak
ArticleOpen Access17 Feb 2026
LRRK2^R1627P mutation amplifies environmental risk factors induced chronic inflammation and α-synuclein aggregation in the gut of rats

Shimin Pang
Jing Lu
Piu Chan
ArticleOpen Access07 Feb 2026
Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onset

Kai Shi Lim
Maria Teresa Periñan
the Global Parkinson’s Genetics Program (GP2)
ArticleOpen Access02 Feb 2026

Announcements

Explore Our Latest Open Collections

We are now accepting submissions to our specialized Collections on Parkinson’s Disease. Contribute your research to advance personalized understanding and treatment. Click to explore Collections open for submission.
Outstanding Reviewers of npj Parkinson's Disease

We are proud to recognize the exceptional contributions of our outstanding reviewers. Their dedication, expertise, and thoughtful evaluations uphold the high standards of npj Parkinson's Disease and play a crucial role in advancing the field. We sincerely thank them for their invaluable service and commitment to scholarly excellence.
Editorial Impact Award from Springer Nature 2025

We are delighted to celebrate Dr. Tansey’s recognition with the Editorial Impact Award 2025 for her outstanding leadership as Editor-in-Chief. This honour reflects a true team effort, made possible by the trust of our authors, editors and the dedication of our reviewers, and represents our shared commitment to the journal community.

Browse articles

Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication

Catarina Serra-Almeida
Javier Jarazo
Jens Christian Schwamborn
ArticleOpen Access31 Mar 2026
In-vivo histology of Parkinson’s disease using quantitative multiparametric mapping

Marta M. Pokotylo
Martin Göttlich
Jannik Prasuhn
ArticleOpen Access31 Mar 2026
Machine learning prediction of discharge destination in patients with Parkinson’s disease; a nationwide cohort study

Hikaru Kamo
Tejas R. Mehta
Christopher W. Hess
ArticleOpen Access28 Mar 2026
O-GlcNAcylation regulates microglial neuroinflammation in Parkinson’s disease

Dong Yeol Kim
Sang-Min Kim
Inn-Oc Han
ArticleOpen Access28 Mar 2026
The genetic spectrum of LRRK2 variants in Parkinson’s disease: findings from a large Chinese cohort

Juan Wan
Hongxu Pan
Qinyong Ye
ArticleOpen Access28 Mar 2026
Physiotherapy interventions for balance impairments in Parkinson’s disease: evidence from a systematic review and dose-response meta-analysis

Rebecca Cardini
Elisa Gervasoni
Matteo Guidetti
ArticleOpen Access25 Mar 2026
Profiling of 5-hydroxymethylcytosine in blood reveals preferential enrichment at exon-intron junctions and predictive value for Parkinson’s disease

Philipp Antczak
Peter Brandt
Kristina Bečanović
ArticleOpen Access20 Mar 2026
Cortical and basal ganglia beta oscillations and frequency-dependent DBS effects in the A53T Parkinson’s disease rat model

Laura Kondrataviciute
Minesh Kapadia
Suneil K. Kalia
ArticleOpen Access19 Mar 2026
Age at onset of Parkinson’s disease modulates the sphingolipid-dopaminergic interplay in autonomic progression

Zhinan Ye
Shishu Zhang
Dehao Yang
ArticleOpen Access19 Mar 2026

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Neuromelanin imaging outperforms free water imaging in diagnosing early Parkinson’s disease: a comparative MRI study

Featured

Detection of alpha-synuclein seeding activity in tear fluid in patients with Parkinson’s disease

Testing an inverse link between limbic alpha-synucleinopathy and myelin markers in mice and humans

LRRK2^R1627P mutation amplifies environmental risk factors induced chronic inflammation and α-synuclein aggregation in the gut of rats

Association of LRRK2 p.A419V with Parkinson’s Disease in East Asians and analysis of age at onset

Announcements

Explore Our Latest Open Collections

Outstanding Reviewers of npj Parkinson's Disease

Editorial Impact Award from Springer Nature 2025

Browse articles

Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication

In-vivo histology of Parkinson’s disease using quantitative multiparametric mapping

Machine learning prediction of discharge destination in patients with Parkinson’s disease; a nationwide cohort study

O-GlcNAcylation regulates microglial neuroinflammation in Parkinson’s disease

The genetic spectrum of LRRK2 variants in Parkinson’s disease: findings from a large Chinese cohort

Physiotherapy interventions for balance impairments in Parkinson’s disease: evidence from a systematic review and dose-response meta-analysis

Profiling of 5-hydroxymethylcytosine in blood reveals preferential enrichment at exon-intron junctions and predictive value for Parkinson’s disease

Cortical and basal ganglia beta oscillations and frequency-dependent DBS effects in the A53T Parkinson’s disease rat model

Age at onset of Parkinson’s disease modulates the sphingolipid-dopaminergic interplay in autonomic progression

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Full Professor in Neuroimmunology at The Salk Institute for Biological Studies

Global Strategic Call for Clinical and Research Talent in Neurology and Neurodegeneration (BBRC)

R&D Specialist in Medical Translational Research - 50%

Junior/senior research technician to support the Holstege lab

Postdoc position in method development in human statistical genetics, with a focus on classificat...

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Meta-analysis of shotgun sequencing of gut microbiota in Parkinson’s disease

O-GlcNAcylation regulates microglial neuroinflammation in Parkinson’s disease

Autophagy dysfunction in iPSCs-derived neurons and midbrain organoids carrying a SNCA triplication

Physiotherapy interventions for balance impairments in Parkinson’s disease: evidence from a systematic review and dose-response meta-analysis

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