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Developmental Biology

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  • Hypoxia-activated scleraxis a mediates epicardial progenitor differentiation into a unique cardiac perivascular cell type
    Bjoern Perder, Yu Xia, Jun Yao, Miaoyan Qiu, Alvin Gea Chen Yao, Muhammad Naeem, Paul Zumbo, Ignace Van der Wee, Avi Yakubov, Kazu Kikuchi, Doron Betel, Todd Evans, Michael R Harrison, Jingli Cao
    bioRxiv 2026.02.26.708296; doi: https://doi.org/10.64898/2026.02.26.708296 New Results
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  • The earliest circadian clock in the mammalian brain emerges in the embryonic choroid plexus
    Helene Vitet, Vuong Hung Truong, Jihwan Myung
    bioRxiv 2025.09.09.675224; doi: https://doi.org/10.1101/2025.09.09.675224 New Results
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  • A Mediator-dependent hypertranscriptional program governs neural stem cell fate decisions in vivo
    Tiago Baptista, Daniela Lopes, Ana Rita Rebelo, Catarina CF Homem
    bioRxiv 2026.02.26.708183; doi: https://doi.org/10.64898/2026.02.26.708183 New Results
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  • Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly
    Kai Ding, Beibei Xu, Xinhao Yu, Xiwen Jia, Taotao Li, Xin Shen, Junda Li, Xudong Cao, Yahui Liu, Zhen Zhang, Yulong He
    bioRxiv 2026.02.26.708190; doi: https://doi.org/10.64898/2026.02.26.708190 New Results
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  • Tissue composition shapes differential skeletal integration strategies during axolotl limb regeneration
    Rita Aires, Sean D. Keeley, Kerstin Brandt, Mário Carreira, Doğa Berşan Güneş, Yagiz Savci, Ulrike Anne Friedrich, Andreas Dahl, Can Aztekin, Tatiana Sandoval-Guzmán
    bioRxiv 2026.02.26.708175; doi: https://doi.org/10.64898/2026.02.26.708175 New Results
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  • Conserved roles of GATA4 and its target gene TBX2 in regulation of human cardiogenesis
    Nicola Graham, Pavel Kirilenko, Ilya Patrushev, Ewan D Fowler, Peter Kille, Michael Gilchrist, Nick D.L. Owens, Branko Latinkic
    bioRxiv 2025.07.11.664341; doi: https://doi.org/10.1101/2025.07.11.664341 New Results
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  • Notch-driven fate asymmetry dictates hair cell behavior via a fate-specific kinase
    Emily Atlas, Caleb C. Reagor, Brian Frost, Sapna Krishnakumar, A. J. Hudspeth, Adrian Jacobo
    bioRxiv 2026.02.25.708020; doi: https://doi.org/10.64898/2026.02.25.708020 New Results
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  • Spinal cord regeneration deploys adult molecular programs that do not recapitulate embryonic development
    Yuxiao Xu, Wenda Zhang, Lili Zhou, Mayssa Mokalled
    bioRxiv 2026.02.25.708028; doi: https://doi.org/10.64898/2026.02.25.708028 New Results
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  • Single-cell-scale spatial transcriptome reveals early regional priming of the developing mouse ovary
    Anthony S Martinez, Tyler J Gibson, Courtney Diamond, Jennifer Jaime, Jennifer McKey
    bioRxiv 2025.09.16.676655; doi: https://doi.org/10.1101/2025.09.16.676655 New Results
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  • Kindlin-2-Moesin interaction orchestrates sprouting angiogenesis via modulating endothelial membrane mechanics and VEGF signaling
    Lu Wang, Yuxin Fu, Zuyang Yu, Yi Lei, Tianjing Yang, Jiayu Liu, Nina Ma, Yuming Liu, Kunfu Ouyang, Kai Zhang, Junhao Hu, Xi Fang, Ying Shen, Jing Zhou, Xiaohong Wang
    bioRxiv 2026.02.24.707842; doi: https://doi.org/10.64898/2026.02.24.707842 New Results
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