Questions tagged [insulin]
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30 questions
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Sympathetic nervous system & insulin release
So basically during the fight or flight response adrenergic receptors start to be activated and both alpha 2 and beta 2 receptors should be stimulated by adrenaline/noradrenaline, why does alpha 2 ...
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Recombinant insulin production and cyanogen bromide action
For recombinant insulin production from E. coli (according to Eli Lilly), cyanogen bromide is used to cleave residues in residual $\beta$-galactosidase. It is well established that cyanogen bromide ...
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Inflammatory effects of glucose from digestion of starch compared to glucose consumed as syrup
Glucose consumed in the form of liquids and as a sweetener added to foods is known to cause various negative health effects, one of which is inflammation. Theres lots of evidence of this, not just in ...
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Using bovine insulin in bovine cell culture for diabetics
Insulin in the US is very expensive. It uses DNA recombinant techniques on yeast or bacteria, which requires patented techniques to isolate the insulin.
In contrast, bovine cell culture of the bovine ...
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Why doesn't the immune system ever destroy the glucagon-producing alpha cells in the pancreas? Why only insulin-making beta cells?
Our pancreas does multiple thing, yet I only ever hear of the beta cells in the Islets of Langerhans being annihilated.
Why is this?
Hmmmm.....
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If insulin secretion is ATP-induced, why don't fatty acids trigger insulin secretion?
I learned in my university physiology course that insulin is released by pancreatic beta-cells in response to glucose that is metabolized and thus increase cellular ATP levels, which in turn close ...
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Why does activity cause hypoglycaemia in diabetics?
(I'm from the UK so I'll be using mmol/L as units and taking <4.0 as hypoglycaemia.)
I remember being told that I should consume a small amount of sugar or reduce insulin dose sightly to increase ...
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How is an extreme insulin overdose counteracted
I just watched this comedy skit that went -
Trainee: I just gave him 10 of insulin
Doctor: 10 what?
Trainee: 10cc
Doctor: * look of terror *
As a diabetic myself I know that 10cc or 1000u is an insane ...
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Why do some people accumulate more diglycerides in their muscle cells?
The scientist Gerald Shulman has experimentally found that young lean adults in their early twenties that are children to people with type 2 diabetes often show muscle insulin resistance. He found ...
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Can monoclonal antibodies be used to transport insulin
Quick question
Monoclonal treatments in cancer require the drug attached to the antibody which then attaches itself to the neoantigen on a cancerous cell, would it be possible to
transport insulin in ...
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How do receptors lose their sensitivity?
Recently, I learned that one of the causes of Type II diabetes is that insulin receptors on cell surfaces lose their sensitivity due to long-term high exposure to insulin (which occurs as a result of ...
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Would intravenous insulin + glucose significantly accelerate glycogen synthesis?
Would an intravenous injection of insulin + glucose result in significantly quicker replenishment of exhausted glycogen stores than an injection of glucose alone?
This is a strictly theoretical ...
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Dangers of excess blood protein? [closed]
Like glucose, amino acids are also insulinogenic as well. So, presumably, just like glucose, the body would also like to keep amino acids levels in the blood stream below (or within) some certain ...
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sweet receptor's affect on insulin release
So I understand the basics of how the body releases insulin to keep blood glucose levels in check and (loosely) that higher insulin levels can lead to more (or at a faster rate) glucose being stored ...
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Full name for stem cells
So during research, my professor mentioned a type of stem cell, a name that was like 5-6 words long, that can be used to treat diabetes by creating an "artificial organ". That hypothetical organ would ...