Questions tagged [malaria]
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29 questions
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Question on Plasmodium presence in RBCs
Malarial parasite can be obtained in RBCs of patient
When temperature reaches normal
An hour before rise in temperature
When temperature rises with rigor
A few hours after temperature reaches normal
...
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How do genetically modified mosquitoes elliminate malaria?
One strategy to eliminate malaria-causing mosquitoes is to release genetically modified male mosquitoes that mate with wild females producing infertile daughters. The problem with this is the presence ...
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Can a symptomatic, recent recipient of live attenuated dengue vaccine Qdenga transfer the virus to mosquitoes if bitten?
Can a symptomatic, recent recipient of live attenuated dengue vaccine QDENGA transfer the virus to mosquitoes if bitten?
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Is it physically impossible for a male Anopheles mosquito to bite?
I know that malaria is spread through female Anopheles mosquitos as they require a blood meal to survive and that male ones do not bite and they survive off of nectar, etc.
But is it physically ...
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Is taking antimalarial drugs a confounder when exposure is "having sprayed insecticide in the house" and the outcome is "malaria infection"
Morning all,
I am curious as to whether the concept of confounding applies in the following situation: Specifically I want to know if "taking antimalarials" is a confounding variable.
The ...
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Which is the best model organism to implement an evolutionary study for P.falciparum?
I have to study and implement some evolutionary statistics for P.falciparum. In your opinion and by your experience, which organism should I consider in order to take the orthologs to implement this ...
2
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1
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Sickle-cell trait : Why is only one type of beta chain found in any one hemoglobin molecule?
I was reading a textbook (iGenetics, 3rd edition page 71), and came across the following passage:
Homozygous bS bS people make Hb-S, the defective hemoglobin, with two
normal a chains specified by ...
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2
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How having sickle cell trait would provide resistance to malarial parasites?
It's mentioned in my textbook that subjects with sickle cell trait develop resistance to malaria. I've read a few research papers predisposing involvement of macrophages and papers asserting ...
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Why is Artemisinin Compound Therapy preferrable over Artemisinin therapy with regards to drug resistance?
How does adding other anti-malarial drugs to artemisinin, to obtain a "combined" therapy result in reducing the frequency of emergence of resistance?
And it is given in the form of artemisinin ...
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1
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Mathematical model for malaria
The simplest malaria model is as follows:
$$\frac{dI}{dt} = \frac{\alpha \beta I}{\alpha I + r} (1-I) - \mu I$$
where $r$ is the natural death rate of mosquitoes, $\mu$ is the death rate of humans, $\...
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Units of parameters in epidemiological model
The simplest malaria model is given by $$\frac{dI}{dt} = \frac{\alpha \beta I}{\alpha I + r} (1-I) - \mu I$$
where $\mu$ is the death rate of humans, $\alpha$ is the transmission rate from humans to ...
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2
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1
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How do sporozoites travel into the human host when the mosquito is sucking blood?
I mean how are the sporozoites able to swim in the reverse direction of blood flow through the proboscis of the mosquito into the human body?
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How long ago did the mutation arise that gives rise to sickle-cell disease?
Is it known how long ago the mutation arose in Africa that gives rise to sickle-cell disease and protects from Malaria in heterozygote carriers?
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1
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Why has malaria only now started to develop resistance against artemisinin?
Why has malaria only now started to develop resistance against artemisinin, considering the compound has been in use for about two millennia in its herbal form in China?
The WHO has reported:
In ...
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First infection of malaria
As I know Plasmodium falciperum survive in either a host animal, human or mosquitoes.
But how does malaria come to infect either of them initially?
I am interested in knowing evolution of malaria. ...
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