Latest research
Contemporary recovery following pediatric powered intracapsular tonsillectomy: a 12-year cohort study
Background Current pediatric tonsillectomy guidelines provide postoperative monitoring and analgesic recommendations largely derived from extracapsular tonsillectomy populations, without addressing intracapsular techniques. Given the distinct...
Pediatricians’ views and attitudes toward phytotherapy: a cross-sectional survey study
Background Although interest in herbal products and complementary medicine practices in pediatric patients has increased, pediatricians’ attitudes toward phytotherapy and the factors associated with these attitudes remain insufficiently defined. This...
Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis
Subcutaneous infliximab is licensed for maintenance only in adults with inflammatory bowel disease, and pediatric evidence sits in small cohorts never pooled. We estimated the effectiveness, pharmacokinetics, immunogenicity, and safety of...
An investigation into the efficacy of treatments for atopic eruption of pregnancy
Atopic eruption of pregnancy (AEP) is a prevalent inflammatory disease in pregnant women and is frequently associated with considerable pruritus and impaired quality of life. There remains an unmet need for reliable tools to predict treatment...
Hypersensitivity Reactions to Biologics: Advances in Diagnosis and Management
Purpose of Review The landscape of biologic therapeutics has expanded to include therapies such as antibody-drug conjugates (ADCs) and bispecific T-cell engagers. As the use of these therapies expands, hypersensitivity reactions (HSRs) can limit the...
Prediction models for early-onset atopic dermatitis in infancy: a prospective cohort study
Background Atopic dermatitis (AD) is the most common chronic inflammatory skin disease in childhood. Early identification of infants at high risk for AD may support preventive interventions and reduce the subsequent burden of allergic diseases. This...
Ultra-low-dose induction phase in oral immunotherapy for children with severe peanut and walnut allergies: a multicenter observational cohort study
Background Peanut and tree nut allergies are increasing worldwide and have become a major cause of anaphylaxis in Japan. Although oral immunotherapy (OIT) is a promising treatment, conventional OIT cannot be initiated in patients with an extremely...
Pediatric orodispersible nanoparticle delivery: recent innovations and practical challenges
Background Designing age-appropriate oral drug-delivery systems remains a major challenge in pharmaceutical sciences. Conventional solid dosage forms are often unsuitable for pediatric patients because of limited swallowing ability, variable dose...
A protocol proposal for safe dental anaesthesia in paediatric patients with allergic backgrounds: insights from a case series of allergic patients
Purpose Paediatric patients with complex allergic backgrounds pose unique challenges in dental treatment requiring local anaesthesia (LA). This report aims to present a structured clinical approach for the dental management of paediatric patients...
Profile of aeroallergens and pulmonary function in cases of chronic rhinosinusitis: a cross-sectional analytical study
Background Chronic rhinosinusitis (CRS) is frequently associated with allergic sensitization and may involve the lower airway as part of the united airway concept. However, region-specific data on aeroallergen profiles and their relationship with...
Exploratory integrative analysis of infant gut microbiome and metabolome suggests diet- and microbiome-derived metabolites associated with childhood asthma
in MetabolomicsBackground Early-life gut microbiome composition has been linked to childhood asthma risk, but the metabolic pathways underlying this association remain unclear. Objective To integrate infant gut microbiome and metabolome data to identify pathways...
Susceptible perinatal windows to arsenic exposure and serum antibody levels in children
Background Several cohorts have documented potential immunotoxic effects of arsenic in pediatric populations, however, the identification of susceptible windows to arsenic exposure remains poorly investigated in relation to vaccine-specific antibody...
Immune Reconstitution in Pediatric Patients Post Autologous Stem Cell Transplantation
Objectives To determine the prevalence of hypogammaglobulinemia at three months post-ASCT and characterize humoral and cellular immune reconstitution kinetics. Methods Twelve pediatric patients (median age 10 y) undergoing ASCT for high-risk...
Thyroid surgery in children: a single pediatric center experience
The increasing incidence of thyroid disease in children requires appropriate training for pediatric surgeons. The specific characteristics of this age group require a different treatment approach from that used in adults.The authors report their...
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Journal
Allergo Journal
Das Allergo Journal ist das offizielle Organ des Ärzteverbands der Deutschen Allergologen e. V. (AeDA) und der Österreichischen Gesellschaft für...
Allergy, Asthma & Clinical Immunology (AACI), the official journal of the Canadian Society of Allergy and Clinical Immunology (CSACI), is an open...
The aim of this journal is to systematically provide the views of highly selected experts on current advances in the fields of allergy and asthma and...
