The first part of the question asks why set theory is generally considered as platonist. I don't think that it is "generally" seen as such; at least not anymore. I'll only address this false (or disputable) assumption.
Platonism is (roughly) the belief that mathematical objects or mathematical structures are real in the sense that they exist independently of the mathematical subject (humans). It is then also the belief that mathematical theorems are true, independent of whether or not they have been verified by us; their truth is not based on a mental construction, but is a discoverable fact of the world. Since these objects and these truths cannot, as such, ever be discovered in the empirical world, platonism then posits that there must be some kind of separate realm of (necessary, a priori) truth(s), in regards to which mathematical theorems are just as true (or even more so) as empirical statements are true of the physical world.
This is an informal philosophical, meta-mathematical belief that is independent of mathematics itself: it's not assumed in any mathematical theory, and it need not be assumed in mathematical practice, though it may have heuristic value if believed. It can also be used to informally justify certain logical principles, for instance LEM, while those who don't accept this belief (for instance intuitionists) may not find such informal justifications unconvincing.
Set theory is a mathematical theory that doesn't require either an affirmation or a negation of platonism. Even the classical form of set theory (ZFC) in which you have axioms like
There is an empty set.
There is an infinite set.
does not require platonism. It's for instance possible to take a formalist stance: we don't need to posit any "objects" in some mysterious, eternal realm, in order to work with those symbols. Or we can take a (related) fictionalist stance: As long as we don't run into inconsistencies, it's fine if we just treat infinite totalities as fictional objects, more or less similar to, say, fictional literary objects, like Hamlet.
If we look at the historical development of set theory (and number theory), then certain mathematical results can also be seen as (informally) undermining a strict platonism, or at least as making it less attractive. In particular the fact that Cantor's Continuum Hypothesis has been proven to be independent of ZFC. Results like that may make the view of a set-theoretic multiverse (Hamkins) seem more plausible, a view that is distinctly anti-platonistic (which btw doesn't make it nominalistic).
The multiverse view in set theory, introduced and argued for in this article, is the view that there are many distinct concepts of set, each instantiated in a corresponding set-theoretic universe. The universe view, in contrast, asserts that there is an absolute background set concept, with a corresponding absolute set-theoretic universe in which every set-theoretic question has a definite answer. The multiverse position, I argue, explains our experience with the enormous diversity of set-theoretic possibilities, a phenomenon that challenges the universe view. In particular, I argue that the continuum hypothesis is settled on the multiverse view by our extensive knowledge about how it behaves in the multiverse, and as a result it can no longer be settled in the manner formerly hoped for.