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Different concentrations of atropine in children with high myopia: a 2-year multicenter double-blind, randomized controlled trial
High myopia in children risks irreversible visual impairment, yet optimal interventions remain debated. This multicenter double-blind,...
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Seafood Allergy: Lessons from Clinical Symptoms, Immunological Mechanisms and Molecular Biology
Food allergy consists of a wide range of disorders that result from adverse immune responses to dietary antigens. Manifestations of allergic...
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Pediatricians’ views and attitudes toward phytotherapy: a cross-sectional survey study
BackgroundAlthough interest in herbal products and complementary medicine practices in pediatric patients has increased, pediatricians’ attitudes...
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Contemporary recovery following pediatric powered intracapsular tonsillectomy: a 12-year cohort study
BackgroundCurrent pediatric tonsillectomy guidelines provide postoperative monitoring and analgesic recommendations largely derived from...
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Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis
Subcutaneous infliximab is licensed for maintenance only in adults with inflammatory bowel disease, and pediatric evidence sits in small cohorts...
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An investigation into the efficacy of treatments for atopic eruption of pregnancy
Atopic eruption of pregnancy (AEP) is a prevalent inflammatory disease in pregnant women and is frequently associated with considerable pruritus and...
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Prediction models for early-onset atopic dermatitis in infancy: a prospective cohort study
BackgroundAtopic dermatitis (AD) is the most common chronic inflammatory skin disease in childhood. Early identification of infants at high risk for...
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Hypersensitivity Reactions to Biologics: Advances in Diagnosis and Management
Purpose of ReviewThe landscape of biologic therapeutics has expanded to include therapies such as antibody-drug conjugates (ADCs) and bispecific...
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Ultra-low-dose induction phase in oral immunotherapy for children with severe peanut and walnut allergies: a multicenter observational cohort study
BackgroundPeanut and tree nut allergies are increasing worldwide and have become a major cause of anaphylaxis in Japan. Although oral immunotherapy...
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Pediatric orodispersible nanoparticle delivery: recent innovations and practical challenges
BackgroundDesigning age-appropriate oral drug-delivery systems remains a major challenge in pharmaceutical sciences. Conventional solid dosage forms...
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A protocol proposal for safe dental anaesthesia in paediatric patients with allergic backgrounds: insights from a case series of allergic patients
PurposePaediatric patients with complex allergic backgrounds pose unique challenges in dental treatment requiring local anaesthesia (LA). This report...
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Profile of aeroallergens and pulmonary function in cases of chronic rhinosinusitis: a cross-sectional analytical study
BackgroundChronic rhinosinusitis (CRS) is frequently associated with allergic sensitization and may involve the lower airway as part of the united...
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Exploratory integrative analysis of infant gut microbiome and metabolome suggests diet- and microbiome-derived metabolites associated with childhood asthma
BackgroundEarly-life gut microbiome composition has been linked to childhood asthma risk, but the metabolic pathways underlying this association...
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Susceptible perinatal windows to arsenic exposure and serum antibody levels in children
BackgroundSeveral cohorts have documented potential immunotoxic effects of arsenic in pediatric populations, however, the identification of...
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Immune Reconstitution in Pediatric Patients Post Autologous Stem Cell Transplantation
ObjectivesTo determine the prevalence of hypogammaglobulinemia at three months post-ASCT and characterize humoral and cellular immune reconstitution...
